Recombinant Human snail family zinc finger 1, His-tagged

• Cat.No.: SNAI1-330H
• Product Overview: SNAI1, 1-264aa, Human, His tag, E.coli

Specification

• Description: Snail homolog 1, also known as SNAI1, is involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Recombinant human SNAI1 protein, fused to His-tag at N-terminus, was expressed in E.coli
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 31.5 kDa (287aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPRSFLV RKPSDPNRKP NYSELQDSNP EFTFQQPYDQ AHLLAAIPPP EILNPTASLP MLIWDSVLAP QAQPIAWASL RLQESPRVAE LTSLSDEDSG KGSQPPSPPS PAPSSFSSTS VSSLEAEAYA AFPGLGQVPK QLAQLSEAKD LQARKAFNCK YCNKEYLSLG ALKMHIRSHT LPCVCGTCGK AFSRPWLLQG HVRTHTGEKP FSCPHCSRAF ADRSNLRAHL QTHSDVKKYQ CQACARTFSR MSLLHKHQES GCSGCPR
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SNAI1 snail homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: SNAI1
• Synonyms: SNAI1; snail homolog 1 (Drosophila); snail 1 (drosophila homolog), zinc finger protein; zinc finger protein SNAI1; SLUGH2; SNA; SNAH; SNAIL; SNAIL1; protein sna; snail 1 homolog; protein snail homolog 1; snail 1 zinc finger protein; snail 1, zinc finger protein; dJ710H13.1
• Gene ID: 6615
• mRNA Refseq: NM_005985
• Protein Refseq: NP_005976
• MIM: 604238
• UniProt ID: O95863
• Chromosome Location: 20q13.2
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met), organism-specific biosystem; Validated targets of C-MYC transcriptional activation, organism-specific biosystem
• Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; kinase binding; metal ion binding; protein binding; sequence-specific DNA binding; zinc ion bindi