Recombinant Human complement factor B, His-tagged
Cat.No. : | CFB-444H |
Product Overview : | CFB, 26- 259aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | CFB is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
Molecular Mass : | 28.4 kDa (257aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSQ SHMTPWSLAR PQGSCSLEGV EIKGGSFRLL QEGQALEYVC PSGFYPYPVQ TRTCRSTGSW STLKTQDQKT VRKAECRAIH CPRPHDFENG EYWPRSPYYN VSDEISFHCY DGYTLRGSAN RTCQVNGRWS GQTAICDNGA GYCSNPGIPI GTRKVGSQYR LEDSVTYHCS RGLTLRGSQR RTCQEGGSWS GTEPSCQDSF MYDTPQEVAE AFLSSLTETI EGVDAEDGHG PGEQQKR |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | CFB complement factor B [ Homo sapiens ] |
Official Symbol : | CFB |
Synonyms : | CFB; complement factor B; B factor, properdin , BF, BFD; H2 Bf; C3 proactivator; C3/C5 convertase; C3 proaccelerator; properdin factor B; B-factor, properdin; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; BF; FB; BFD; GBG; CFAB; PBF2; AHUS4; FBI12; H2-Bf; FLJ54899; |
Gene ID : | 629 |
mRNA Refseq : | NM_001710 |
Protein Refseq : | NP_001701 |
UniProt ID : | P00751 |
Chromosome Location : | 6p21.3 |
Pathway : | Activation of C3 and C5, organism-specific biosystem; Alternative complement activation, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; |
Function : | complement binding; peptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
Cfb-1085M | Recombinant Mouse Cfb Protein, MYC/DDK-tagged | +Inquiry |
CFB-756H | Recombinant Human CFB Protein, His-tagged | +Inquiry |
CFB-334H | Recombinant Human CFB Protein, His-tagged | +Inquiry |
CFB-583H | Recombinant Human CFB Protein, His (Fc)-Avi-tagged | +Inquiry |
CFB-1164M | Recombinant Mouse CFB Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CFB-104H | Native Human Factor B | +Inquiry |
◆ Lysates | ||
CFB-7558HCL | Recombinant Human CFB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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