Recombinant Human MARCKS-like 1, His-tagged
Cat.No. : | MARCKSL1-526H |
Product Overview : | MARCKSL1, 1-195aa , Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | MARCKS-related protein, also known as MARCKSL1, is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indicator of PKC activation. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading. Recombinant human MARCKSL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol |
Molecular Mass : | 21.9kDa (218aa) confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMGSQSSK APRGDVTAEE AAGASPAKAN GQENGHVKSN GDLSPKGEGE SPPVNGTDEA AGATGDAIEP APPSQGAEAK GEVPPKETPK KKKKFSFKKP FKLSGLSFKR NRKEGGGDSS ASSPTEEEQE QGEIGACSDE GTAQEGKAAA TPESQEPQAK GAEASAASEE EAGPQATEPS TPSGPESGPT PASAEQNE |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by BCA assay) |
Gene Name : | MARCKSL1 MARCKS-like 1 [ Homo sapiens ] |
Official Symbol : | MARCKSL1 |
Synonyms : | MARCKSL1; MARCKS-like 1; MARCKS like protein , MLP; MARCKS-related protein; F52; MacMARCKS; MLP1; mac-MARCKS; MARCKS-like protein 1; macrophage myristoylated alanine-rich C kinase substrate; MLP; MRP; MACMARCKS; |
Gene ID : | 65108 |
mRNA Refseq : | NM_023009 |
Protein Refseq : | NP_075385 |
MIM : | 602940 |
UniProt ID : | P49006 |
Chromosome Location : | 1p35.1 |
Pathway : | Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Leishmaniasis, organism-specific biosystem; Leishmaniasis, conserved biosystem; |
Function : | calmodulin binding; |
Products Types
◆ Recombinant Protein | ||
MARCKSL1-3243R | Recombinant Rat MARCKSL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MARCKSL1-2503R | Recombinant Rhesus Macaque MARCKSL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MARCKSL1-1764H | Recombinant Human MARCKSL1 Protein, His&GST-tagged | +Inquiry |
MARCKSL1-3208H | Recombinant Human MARCKSL1 protein, GST-tagged | +Inquiry |
MARCKSL1-3613C | Recombinant Chicken MARCKSL1 | +Inquiry |
◆ Lysates | ||
MARCKSL1-4466HCL | Recombinant Human MARCKSL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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