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Recombinant Human ubiquitin-conjugating enzyme E2G 1, His-tagged

Cat.No. : UBE2G1-667H
Product Overview : UBE2G1, 1-170aa Human, His tag, E.coli
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Description : The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UE2G1 is a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. Recombinant human UBE2G1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In Phosphate buffered saline (pH7.4) containing, 30% glycerol, 1mM DTT
Molecular Mass : 21.9kDa (193aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMTELQSA LLLRRQLAEL NKNPVEGFSA GLIDDNDLYR WEVLIIGPPD TLYEGGVFKA HLTFPKDYPL RPPKMKFITE IWHPNVDKNG DVCISILHEP GEDKYGYEKP EERWLPIHTV ETIMISVISM LADPNGDSPA NVDAAKEWRE DRNGEFKRKV ARCVRKSQET AFE
Purity : >95% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : UBE2G1 ubiquitin-conjugating enzyme E2G 1 [ Homo sapiens ]
Official Symbol : UBE2G1
Synonyms : UBE2G1; ubiquitin-conjugating enzyme E2G 1; UBE2G, ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G1; UBC7; ubiquitin-protein ligase G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); E217K; UBE2G;
Gene ID : 7326
mRNA Refseq : NM_003342
Protein Refseq : NP_003333
MIM : 601569
UniProt ID : P62253
Chromosome Location : 17p13.2
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Function : ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is UBE2G1 associated with cardiovascular disease? 11/30/2022

Studies have shown that UBE2G1 may be associated with the onset of cardiovascular diseases such as atherosclerosis and myocardial infarction.

What is the current state of development for UBE2G1? 10/12/2022

Drug development for UBE2G1 is currently in clinical trials, including small molecule inhibitors against UBE2G1 and inhibitors against the UBE2G1 signaling pathway.

How can I increase the expression level of UBE2G1? 07/11/2021

There is no direct way to increase the expression level of UBE2G1, but it can be improved by regulating gene expression and providing nutritional support.

What is the relationship between UBE2G1 and viral infection? 05/27/2020

Studies have shown that UBE2G1 can be involved in the regulation of antiviral immune responses and affect the course of viral infection.

What is the relationship between UBE2G1 and autoimmune diseases? 03/10/2020

UBE2G1 plays an important role in the pathogenesis of certain autoimmune diseases.

How can UBE2G1 be used as a biomarker in clinical practice? 12/05/2019

In clinical practice, the expression level of UBE2G1 can be measured to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of cancer, measuring the expression level of UBE2G1 can help doctors determine the type, stage and prognosis of the disease, and guide the choice of treatment plan.

Customer Reviews (3)

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Reviews
06/12/2022

    The experimental results using UBE2G1 are accurate and reliable, and the data are highly scientific.

    03/05/2022

      UBE2G1 has high yield and good economic benefits.

      05/31/2021

        The price is reasonable and the quality is very good. I'm very satisfied.

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