Recombinant Human ubiquitin-conjugating enzyme E2G 1, His-tagged
Cat.No. : | UBE2G1-667H |
Product Overview : | UBE2G1, 1-170aa Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UE2G1 is a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. Recombinant human UBE2G1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In Phosphate buffered saline (pH7.4) containing, 30% glycerol, 1mM DTT |
Molecular Mass : | 21.9kDa (193aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMTELQSA LLLRRQLAEL NKNPVEGFSA GLIDDNDLYR WEVLIIGPPD TLYEGGVFKA HLTFPKDYPL RPPKMKFITE IWHPNVDKNG DVCISILHEP GEDKYGYEKP EERWLPIHTV ETIMISVISM LADPNGDSPA NVDAAKEWRE DRNGEFKRKV ARCVRKSQET AFE |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | UBE2G1 ubiquitin-conjugating enzyme E2G 1 [ Homo sapiens ] |
Official Symbol : | UBE2G1 |
Synonyms : | UBE2G1; ubiquitin-conjugating enzyme E2G 1; UBE2G, ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G1; UBC7; ubiquitin-protein ligase G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); E217K; UBE2G; |
Gene ID : | 7326 |
mRNA Refseq : | NM_003342 |
Protein Refseq : | NP_003333 |
MIM : | 601569 |
UniProt ID : | P62253 |
Chromosome Location : | 17p13.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem; |
Function : | ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
UBE2G1-6056R | Recombinant Rat UBE2G1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2G1-0034H | Recombinant Human UBE2G1 Protein (T2-E170), His/Strep tagged | +Inquiry |
Ube2g1-6787M | Recombinant Mouse Ube2g1 Protein, Myc/DDK-tagged | +Inquiry |
UBE2G1-9828M | Recombinant Mouse UBE2G1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2G1-0033H | Recombinant Human UBE2G1 Protein (T2-E170), Tag Free | +Inquiry |
◆ Lysates | ||
UBE2G1-579HCL | Recombinant Human UBE2G1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionStudies have shown that UBE2G1 may be associated with the onset of cardiovascular diseases such as atherosclerosis and myocardial infarction.
Drug development for UBE2G1 is currently in clinical trials, including small molecule inhibitors against UBE2G1 and inhibitors against the UBE2G1 signaling pathway.
There is no direct way to increase the expression level of UBE2G1, but it can be improved by regulating gene expression and providing nutritional support.
Studies have shown that UBE2G1 can be involved in the regulation of antiviral immune responses and affect the course of viral infection.
UBE2G1 plays an important role in the pathogenesis of certain autoimmune diseases.
In clinical practice, the expression level of UBE2G1 can be measured to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of cancer, measuring the expression level of UBE2G1 can help doctors determine the type, stage and prognosis of the disease, and guide the choice of treatment plan.
Customer Reviews (3)
Write a reviewThe experimental results using UBE2G1 are accurate and reliable, and the data are highly scientific.
UBE2G1 has high yield and good economic benefits.
The price is reasonable and the quality is very good. I'm very satisfied.
Ask a Question for All UBE2G1 Products
Required fields are marked with *
My Review for All UBE2G1 Products
Required fields are marked with *
Inquiry Basket