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Recombinant Human CD1D & B2M protein, His-tagged

Cat.No. : CD1D & B2M-250H
Product Overview : Recombinant Human CD1D & B2M protein(P15813 & P61769)(Met1-Ser301 & Met1-Met119), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The recombinant heterodimer of human CD1D/B2M comprises 393 (293+100) amino acids and has a calculated molecular mass of 45 (33.3+ 11.7) KDa. The apparent molecular mass of rh CD1D/B2M heterodimer is approximately 43.2 and 12.5 KDa respectively in SDS-PAGE under reducing conditions.
Protein Length : Met1-Ser301 & Met1-Met119
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD1D CD1d molecule [ Homo sapiens ]
Official Symbol : CD1D
Synonyms : CD1D; CD1d molecule; CD1d antigen , CD1D antigen, d polypeptide; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; R3; CD1A; MGC34622;
Gene ID : 912
mRNA Refseq : NM_001766
Protein Refseq : NP_001757
MIM : 188410
UniProt ID : P15813

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any drugs targeting CD1D in development? 12/17/2022

Some pharmaceutical companies are researching and developing drugs that target CD1D for therapeutic purposes, although these are still in the early stages of development.

How is CD1D involved in lipid antigen presentation? 06/21/2022

CD1D binds and presents lipid antigens to NKT cells, facilitating immune responses against pathogens or aberrant cells.

How does CD1D differ from other antigen-presenting proteins like MHC? 02/20/2022

CD1D primarily presents lipid antigens, while major histocompatibility complex (MHC) proteins present peptide antigens. CD1D is crucial for lipid-specific immune responses.

In which diseases is CD1D deficiency implicated? 10/27/2020

CD1D deficiency has been associated with an increased susceptibility to certain infections and a potential link to autoimmune disorders.

Are there any clinical trials targeting CD1D? 02/04/2018

Yes, several clinical trials are exploring the modulation of CD1D in various diseases, including cancer and autoimmune disorders, to assess its therapeutic potential.

Customer Reviews (3)

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Reviews
03/14/2020

    The CD1D protein's versatility allows it to be effectively employed in various experimental designs, further enhancing its suitability for diverse research needs.

    02/27/2020

      Their extensive knowledge and expertise can help troubleshoot issues or provide guidance on experimental design, enabling you to overcome obstacles and achieve your research goals.

      04/15/2016

        In protein electron microscopy structure analysis, the CD1D protein demonstrates outstanding performance.

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