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Active Recombinant Human CD48 protein, hFc-tagged

Cat.No. : CD48-252H
Product Overview : Recombinant Human CD48 protein(NP_001769.2)(Met1-Ser220), fused with hFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : hFc
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : 1. Measured by its binding ability in a functional ELISA.2. Immobilized human 2B4-His, at 10 μg/mL (100 μL/well) can bind human CD48-Fc. The EC50 of human CD48-Fc is 0.03-0.06μg/mL.
Molecular Mass : The recombinant human CD48/Fc comprises 432 amino acids and has a predicted molecular mass of 49.1 kDa. The apparent molecular mass of the protein is approximately 64.5 kDa in SDS-PAGE under reducing conditions.
Protein Length : Met1-Ser220
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 90 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : CD48 CD48 molecule [ Homo sapiens ]
Official Symbol : CD48
Synonyms : CD48; CD48 molecule; BCM1, CD48 antigen (B cell membrane protein) , CD48 molecule; CD48 antigen; BLAST; hCD48; mCD48; SLAMF2; TCT.1; BCM1 surface antigen; leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen (B-cell membrane protein); BCM1; BLAST1; MEM-102;
Gene ID : 962
mRNA Refseq : NM_001256030
Protein Refseq : NP_001242959
MIM : 109530
UniProt ID : P09326

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Could the expression level of CD48 protein be modulated to treat disease? 11/02/2022

There is currently no treatment that directly regulates CD48 protein expression levels. However, by regulating the function of the immune system, the expression level of CD48 protein can be indirectly affected to treat some diseases.

How does the expression level of CD48 protein relate to the prognosis of tumors? 10/06/2022

Expression level of CD48 protein is associated with the prognosis of certain tumors. In some cancers, high levels of CD48 protein expression may predict a poor prognosis.

How does CD48 protein relate to the immune system? 04/16/2022

CD48 protein is an important molecule in the immune system that is involved in the activation and differentiation of lymphocytes and phagocytes, as well as inflammation and tissue repair. Its expression levels may affect the function of the immune system.

Does the level of CD48 protein expression correlate with vaccine efficacy? 06/09/2020

Studies have shown that the expression level of CD48 protein may affect the effectiveness of vaccination. In some cases, high levels of CD48 protein expression may suppress the immune response, thus affecting the effectiveness of vaccination.

Can CD48 protein be used as a biomarker for tumors? 03/26/2020

Yes, the CD48 protein can be used as a biomarker for some tumors. Studies have shown that in some cancers, high levels of CD48 protein expression may predict tumor growth and metastasis.

How does the expression level of CD48 protein relate to the occurrence and progression of the disease? 12/02/2019

Studies have shown that the expression level of CD48 protein may be associated with the occurrence and progression of certain diseases. For example, in some cancers, the expression level of the CD48 protein may affect the growth and metastasis of the tumor.

Customer Reviews (3)

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Reviews
09/25/2022

    The anti-interference ability in Western blot is very strong, which can effectively resist the influence of endogenous interference factors.

    05/14/2021

      High safety, high expression level, ideal for laboratory and practical applications.

      02/18/2021

        Low preparation cost, high cost performance, saving funds, very suitable for our research.

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