Recombinant Human NPC2, His-tagged

• Cat.No.: NPC2-349H
• Product Overview: A DNA sequence encoding the human NPC2 (NP_006423.1) (Met1-Leu151) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Source: Human Cells
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human NPC2 consists of 143 amino acids and predicts a molecular mass of 16 KDa. It migrates as an approximately 18-24 KDa band in SDS-PAGE under reducing conditions.
• Protein length: Met1-Leu151
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: NPC2 Niemann-Pick disease, type C2 [ Homo sapiens ]
• Official Symbol: NPC2
• Synonyms: NPC2; Niemann-Pick disease, type C2; epididymal secretory protein E1; EDDM1; epididymal protein 1; HE1; NP C2; tissue-specific secretory protein; human epididymis-specific protein 1; niemann-Pick disease type C2 protein; MGC1333
• Gene ID: 10577
• mRNA Refseq: NM_006432
• Protein Refseq: NP_006423
• MIM: 601015
• UniProt ID: P61916
• Chromosome Location: 14q24.3
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: cholesterol binding; enzyme binding