Active Recombinant Human Il23R, MIgG2a Fc-tagged

• Cat.No.: Il23R-8615H
• Product Overview: The extracellular domain of human IL-23R (NP_653302.2) (Gly24-Asp353) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell

Specification

• Description: IL23R (interleukin 23 receptor) is a protein-coding gene. Diseases associated with IL23R include inflammatory bowel disease 17, protection against, and psoriasis, protection against, and among its related super-pathways are STAT3 Pathway and Immune response IL-23 signaling pathway. GO annotations related to this gene include interleukin-23 receptor activity and interleukin-12 receptor binding.
• Source: CHO cell
• Species: Human
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.
• Molecular Mass: 64KDa (monomer)
• AA Sequence: Gly24-Asp353
• Endotoxin: <0.06 eu/μg as determined by lal>
• Purity: >98%, by SDS-PAGE under reducing conditions
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: IL23R interleukin 23 receptor [ Homo sapiens ]
• Official Symbol: IL23R
• Synonyms: IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor
• Gene ID: 149233
• mRNA Refseq: NM_144701
• Protein Refseq: NP_653302
• MIM: 607562
• UniProt ID: Q5VWK5
• Chromosome Location: 1p31.2
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL23-mediated signaling events, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 binding; contributes_to interleukin-23 receptor activity; receptor activity