"AFP" Related Products

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Native Human fetal cord serum

Cat.No.: AFP-3017H
Product Overview: a-fetoprotein (AFP)
Description: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
Source: Human fetal cord serum
Species: Human
Form: Lyophilised powder from 0.1 M PBS, pH 7.4 - 7.6
Molecular Mass: 68,678 Da
Protein length: 609
Purity: Purity >98 % (SDS-PAGE)
Applications: Immunoassay
Notes: Small volumes of AFP protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage: Store at -20 degree C.
Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name: AFP alpha-fetoprotein [ Homo sapiens ]
Official Symbol: AFP
Synonyms: AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein;
Gene ID: 174
mRNA Refseq: NM_001134
Protein Refseq: NP_001125
UniProt ID: P02771
Chromosome Location: 4q11-q13
Pathway: Direct p53 effectors, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem;
Function: metal ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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