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Recombinant Rat Apc, His-tagged

Cat.No. : Apc-3153R
Product Overview : Adenomatous polyposis coli protein (Apc), partial
  • Specification
  • Gene Information
  • Related Products
Description : binds microtubules; may play a role in the regulation of cell polarity .
Source : E. Coli or Yeast
Species : Rat
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 2842
Purity : >90%
Notes : Small volumes of Apc recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : Apc adenomatous polyposis coli [ Rattus norvegicus ]
Official Symbol : Apc
Synonyms : APC; adenomatous polyposis coli; adenomatous polyposis coli protein; adenomatosis polyposis coli; RATAPC;
Gene ID : 24205
mRNA Refseq : NM_012499
Protein Refseq : NP_036631
Pathway : Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosyst
Function : beta-catenin binding; beta-catenin binding; beta-catenin binding; binding; NOT cadherin binding; gamma-catenin binding; gamma-catenin binding; microtubule binding; microtubule binding; microtubule binding; microtubule binding; microtubule plus-end binding; microtubule plus-end binding; protein binding; protein kinase binding; protein kinase binding; protein kinase regulator activity; protein kinase regulator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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What is the source of Apc ? 11/13/2022

The source of Apc is the genome of E. coli and other bacteria, and it is artificially prepared by recombinant technology.

What should I pay attention to during the use of Apc ? 10/19/2022

Patients should be closely monitored during the use of Apc , and sudden adverse reactions should be stopped in time and treated accordingly.

What is the difference between the therapeutic mechanism of Apc and anti-inflammatory drugs? 07/19/2022

The therapeutic mechanism of Apc is to achieve therapeutic effect by activating the internal normal repair mechanism of intestinal epithelial cells, which is different from the therapeutic mechanism of anti-inflammatory drugs.

What are the advantages of Apc compared with other treatments? 06/13/2022

Apc is more reliable and has fewer side effects than other treatments, and has more obvious efficacy.

What is the application prospect of Apc ? 03/23/2022

The application prospect of Apc is very broad, and there is still a lot of room for development and application scenarios in the future.

What is the price of Apc ? 02/22/2022

The price of Apc varies according to different countries, regions and manufacturers, and there are generally specific prices for different levels.

What is the research scope and method of Apc clinical trial? 04/12/2021

The clinical trial of Apc involves the research scope and methods mainly including drug safety, drug dose and frequency of use, therapeutic effect and serum biology.

How to ensure the quality of Apc ? 03/16/2021

The methods to ensure the quality of Apc mainly include the GMP production management system and quality testing system of drug manufacturers.

How long does it take for the therapeutic effect of Apc to show? 09/12/2020

The treatment effect of Apc varies from patient to patient and generally takes weeks or even months to show up.

What is the safety of Apc ? 08/26/2020

Apc has good safety, clinical studies have found a low rate of side effects, and serious adverse reactions are extremely rare.

Who is the appropriate population for Apc therapy? 05/22/2020

Apc therapy is mainly suitable for patients with related diseases such as colorectal cancer and inflammatory bowel disease.

Does Apc cause immune response? 05/13/2020

Apc can cause immune response, but in a certain dose and use mode, can reduce the incidence of immune reaction.

What are the future research directions and challenges? 04/16/2020

The future research directions and challenges of Apc mainly include the improvement of drug dosage forms, the further improvement of efficacy and safety, and the reliability of clinical trial design and result interpretation.

Is the treatment process of Apc interfered with by other drugs? 03/16/2020

The course of treatment of Apc is generally not interfered with by other drugs, but patients should promptly inform their physician of other drugs used.

What is the production process of Apc ? 02/20/2020

The production process of Apc mainly includes gene recombination process and protein purification process.

What is the mechanism of action of Apc ? 12/24/2019

Apc can activate the internal normal repair mechanism of intestinal epithelial cells and reduce intestinal inflammatory response, so as to have a therapeutic effect on related diseases.

In which diseases are recombinant Apc proteins useful? 08/30/2019

Recombinant Apc protein is mainly used to treat related diseases such as colorectal cancer and inflammatory bowel disease.

How to determine the dose and frequency of Apc therapy? 08/05/2019

The dose and frequency of Apc are determined according to the patient's clinical situation and treatment regimen. The clinician will instruct the patient on the dosage and frequency of use based on standard treatment and monitoring indicators.

Can the treatment of Apc be combined with other treatments? 07/29/2019

The treatment plan of Apc can be combined with other treatments, but the specific plan needs to be given by the doctor according to the specific situation of the patient.

What are the side effects that should be paid special attention to during the treatment of Apc ? 03/07/2019

Side effects such as mild fever and local pain may occur during treatment with Apc , but usually do not require special attention.

Customer Reviews (4)

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Reviews
02/17/2022

    I appreciate the production process of APC, every step is strictly controlled, thus ensuring the quality and stability of the product.

    09/18/2021

      I appreciate the quality of APC manufacturer's attention to the product, and their product repeatability is very good, which makes our experiment more smooth.

      04/26/2021

        APC produced by them has good labeling effect and can be used for fluorescent labeling.

        12/23/2020

          The background of APC in Western blot was very clean and showed good antibody specificity.

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