Recombinant Human DVL2, GST-tagged
| Cat.No. : |
DVL2-108H |
| Product Overview : |
Recombinant Human DVL2 was expressed as gst-tagged fusion protein by E.Coli and purified by GSH-sepharose. |
- Specification
- Gene Information
- Related Products
| Description : |
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. |
| Source : |
E.coli |
| Species : |
Human |
| Tag : |
GST |
| Protein length : |
False |
| AA Sequence : |
N-term-340aa |
| Storage : |
The protein is stored in PBS buffer at -20 oC. Repeated freeze-thaw cycles should be avoided. |
| Concentration : |
1.0mg/ml |
| Storage Buffer : |
1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name : |
DVL2 dishevelled, dsh homolog 2 (Drosophila) [ Homo sapiens ] |
| Official Symbol : |
DVL2 |
| Synonyms : |
DVL2; dishevelled, dsh homolog 2 (Drosophila); dishevelled 2 (homologous to Drosophila dsh); segment polarity protein dishevelled homolog DVL-2; dishevelled 2 (homologous to Drosophila dsh); Dishevelled dsh homolog 2; Dishevelled-2; Dishevelled2; DSH homolog 2; DVL 2; Dvl2; DVL2_HUMAN; Segment polarity protein dishevelled homolog DVL 2; Segment polarity protein dishevelled homolog DVL-2; Segment polarity protein dishevelled homolog DVL2; DSH homolog 2; dishevelled-2; OTTHUMP00000128349 |
| Gene ID : |
1856 |
| mRNA Refseq : |
NM_004422 |
| Protein Refseq : |
NP_004413 |
| MIM : |
602151 |
| UniProt ID : |
O14641 |
| Chromosome Location : |
17p13.1 |
| Pathway : |
Basal cell carcinoma; Canonical Wnt signaling pathway; DNA damage response (only ATM dependent) |
| Function : |
frizzled binding; identical protein binding; protein binding; protein domain specific binding; protein self-association |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
