Active Recombinant Mouse IL1RL1, HIgG1 Fc-tagged

• Cat.No.: IL1RL1-505H
• Product Overview: The extracellular domain of human IL-33R[ST2] (AAH30975.1) (Lys19-Phe328) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.

Specification

• Description: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene inmouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the functionof helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) andinterleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome2q12. Alternative splicing of this gene results in multiple transcript variants
• Source: CHO cell
• Species: Human
• Tag: HIgG1 Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to bind Recombinant Human IL‑33 in a functional ELISA.
• Molecular Mass: 61KDa (monomer)
• AA Sequence: Lys19-Phe328
• Endotoxin: <0.06 eu/μg as determined by lal>
• Purity: >98%, by SDS-PAGE under reducing conditions
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: IL1RL1 interleukin 1 receptor-like 1 [ Homo sapiens ]
• Official Symbol: IL1RL1
• Synonyms: IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623
• Gene ID: 9173
• mRNA Refseq: NM_003856
• Protein Refseq: NP_003847
• MIM: 601203
• UniProt ID: Q01638
• Chromosome Location: 2q12
• Function: cytokine receptor activity; interleukin-1 receptor activity; interleukin-33 binding; protein binding; receptor activity; receptor signaling protein activity