Active Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged

• Cat.No.: IL33-130M
• Product Overview: The extracellular domain of mouse IL-33 (NP_001158196.1)(Gln118-Ile266) is fused to the N-terminus of the Fc region of a mouse IgG2a was expressed in CHO cell.

Specification

• Description: IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2(Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1family receptor that is selectively expressed on Th2 cells and mast cells
• Source: CHO cell
• Species: Mouse
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured in a cell proliferation assay.
• Molecular Mass: 43KDa (monomer)
• AA Sequence: Gln118-Ile266
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Il33 interleukin 33 [ Mus musculus ]
• Official Symbol: IL33
• Synonyms: IL33; interleukin 33; interleukin-33; nuclear factor from high endothelial venules; Il-33; Il1f11; NF-HEV; 9230117N10Rik
• Gene ID: 77125
• mRNA Refseq: NM_001164724
• Protein Refseq: NP_001158196
• Pathway: Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem
• Function: cytokine activity; cytokine activity; cytokine activity