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Home > Products > Recombinant Proteins > Recombinant Human BMP4, HIgG1 Fc-tagged, mutant

Recombinant Human BMP4, HIgG1 Fc-tagged, mutant

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Cat.No.:
BMP4-24H
Product Overview:
The extracellular domain of human BMP-4 (NP_001193.2) (Ser293-Arg408) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description:
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5" untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Source:
CHO cells
Species:
Human
Tag:
HIgG1 Fc-tagged, mutant
Form:
Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity:
Measured by its ability to induce alkaline phosphatase production .
Molecular Mass:
39KDa (monomer)
AA Sequence:
Ser293-Arg408
Endotoxin:
<0.06 eu/μg as determined by lal test.>
Purity:
>98%, by SDS-PAGE under reducing conditions.
Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution:
Reconstitute at 100μg/ml in sterile PBS.
Warning:
Avoid freeze/thaw cycles.


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Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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