Active Recombinant Human CD40LG, MIgG2a Fc-tagged
Cat.No. : | CD40LG-34H |
Product Overview : | The extracellular domain of human CD40L (NP_000065.1) (Met113-Leu261) is fused to the N-terminus of the Fc portion of mouse IgG2a was expressed in CHO celL |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. |
Source : | CHO cells |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured in a cell proliferation assay using enriched human B cells in the presence of IL-4. |
Molecular Mass : | 46 KDa (monomer) |
AA Sequence : | Met113-Leu261 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CD40LG CD40 ligand [ Homo sapiens ] |
Official Symbol : | CD40LG |
Synonyms : | CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5; |
Gene ID : | 959 |
mRNA Refseq : | NM_000074 |
Protein Refseq : | NP_000065 |
MIM : | 300386 |
UniProt ID : | P29965 |
Chromosome Location : | Xq26 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; |
Function : | CD40 receptor binding; cytokine activity; tumor necrosis factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
CD40LG-0818H | Recombinant Human CD40LG Protein, GST-Tagged | +Inquiry |
CD40LG-02R | Recombinant Rabbit CD40LG Protein | +Inquiry |
CD40LG-567R | Recombinant Rhesus Macaque CD40LG Protein, His (Fc)-Avi-tagged | +Inquiry |
CD40LG-636M | Recombinant Mouse CD40LG Protein | +Inquiry |
Cd40lg-2063M | Active Recombinant Mouse Cd40lg Protein | +Inquiry |
◆ Lysates | ||
CD40LG-1965HCL | Recombinant Human CD40LG cell lysate | +Inquiry |
CD40LG-1548MCL | Recombinant Mouse CD40LG cell lysate | +Inquiry |
CD40LG-1080CCL | Recombinant Cynomolgus CD40LG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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