Active Recombinant Human CD27, MIgG2a Fc-tagged
Cat.No. : | CD27-001H |
Product Overview : | The extracellular domain of human CD27[TNFRSF7] (AAH12160.1)( Thr21- Ile192) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO celL |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required forgeneration and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role inregulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to theactivation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signalingprocess of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and isthought to play an important role in the apoptosis induced by this receptor. |
Source : | CHO cells |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit the proliferation of mouse T cells induced by CD27 Ligand and anti-CD3. |
Molecular Mass : | 45 KDa (monomer) |
AA Sequence : | Thr21- Ile192 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CD27 CD27 molecule [ Homo sapiens ] |
Official Symbol : | CD27 |
Synonyms : | CD27; CD27 molecule; TNFRSF7, tumor necrosis factor receptor superfamily, member 7; CD27 antigen; S152; Tp55; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7; T14; TNFRSF7; MGC20393; |
Gene ID : | 939 |
mRNA Refseq : | NM_001242 |
Protein Refseq : | NP_001233 |
MIM : | 186711 |
UniProt ID : | P26842 |
Chromosome Location : | 12p13 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein binding; receptor activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD27-1345H | Acitve Recombinant Human CD27 protein(Met1-Ile192), His-tagged | +Inquiry |
Cd27-365M | Recombinant Mouse Cd27 Protein, His&GST-tagged | +Inquiry |
CD27-947R | Recombinant Rat CD27 Protein (Met1-Cys181), MlgG2a Fc-tagged | +Inquiry |
Cd27-2058M | Recombinant Mouse Cd27 Protein, Myc/DDK-tagged | +Inquiry |
Cd27-23R | Recombinant Rat Cd27 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD27-2415MCL | Recombinant Mouse CD27 cell lysate | +Inquiry |
CD27-1383HCL | Recombinant Human CD27 cell lysate | +Inquiry |
CD27-001HCL | Recombinant Human CD27 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket