Active Recombinant Mouse CCL2, MIgG2a Fc-tagged

• Cat.No.: CCL2-1679M
• Product Overview: The extracellular domain of mouse CCL2 (NP_035463.1) (Gln24-Asn148) is fused to the N-terminus of the Fc portion of mouse IgG2a was expressed in CHO cell.

Specification

• Source: CHO cells
• Species: Mouse
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR2A
• Molecular Mass: 40 kDa
• AA Sequence: Gln24-Asn148
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: ≥98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus ]
• Official Symbol: CCL2
• Synonyms: CCL2; chemokine (C-C motif) ligand 2; C-C motif chemokine 2; small inducible cytokine A2; small-inducible cytokine A2; monocyte chemotactic protein 1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; platelet-derived growth factor-inducible protein JE; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
• Gene ID: 20296
• mRNA Refseq: NM_011333
• Protein Refseq: NP_035463
• Pathway: Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem
• Function: CCR2 chemokine receptor binding; CCR2 chemokine receptor binding; G-protein coupled receptor binding; chemokine activity; cytokine activity; heparin binding; protein binding