Active Recombinant Rat HMGB1, HIgG1 Fc-tagged

• Cat.No.: HMGB1-001R
• Product Overview: The extracellular domain of rat HMGB1(NP_037095.1) (Arg24-Glu215) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.

Specification

• Source: CHO cells
• Species: Rat
• Tag: HIgG1 Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured in a competitive binding assay.
• Molecular Mass: 50KDa
• AA Sequence: Arg24-Glu215
• Endotoxin: <0.06 eu/μg as determined by lal>
• Purity: ≥98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Hmgb1 high mobility group box 1 [ Rattus norvegicus ]
• Official Symbol: HMGB1
• Synonyms: HMGB1; high mobility group box 1; high mobility group protein B1; HMG-1; amphoterin; high mobility group 1; heparin-binding protein p30; high mobility group protein 1; Hmg1; Ac2-008; MGC93598; MGC93599
• Gene ID: 25459
• mRNA Refseq: NM_012963
• Protein Refseq: NP_037095
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem
• Function: 5S rRNA binding; DNA binding, bending; DNA binding, bending; RAGE receptor binding; RAGE receptor binding; bent DNA binding; calcium-dependent protein kinase regulator activity; crossed form four-way junction DNA binding; cytokine activity; cytokine activ