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Active Recombinant Mouse Il12a&Ebi3, HIgG1 Fc-tagged

Cat.No. : Il12a&Ebi3-110M
Product Overview : A soluble dimeric fusion protein consisting of the extracellular domain of Mouse IL12a subunit (NP_032377.1)(Arg23-Ala215) was fused to human IgG1 Fc, and the mouse Ebi3 subunit (NP_056581.1)(Ala23-Pro228) linked to IL12a by disulfide bonds.
  • Specification
  • Gene Information
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Source : CHO cells
Species : Mouse
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Bioactivity was measured in a cell proliferation assay of Con A activated mouse splenocytes.
Molecular Mass : 46kDa and 23kDa (monomer)
AA Sequence : A soluble dimeric fusion protein consisting of the extracellular domain of Mouse IL12a subunit (NP_032377.1)(Arg23-Ala215) was fused to human IgG1 Fc, and the mouse Ebi3 subunit (NP_056581.1)(Ala23-Pro228) linked to IL12a by disulfide bonds.
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Il12a&Ebi3
Official Symbol : IL35
Synonyms : p35; Ll12a; Il-12a; IL-12p35; EBI-3; IL-27
Gene ID : 16159 & 50498
mRNA Refseq : NM_001159424&NM_015766
Protein Refseq : NP_001152896& NP_056581

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the dosage of IL35? 11/03/2022

The dosage of IL35 is usually determined in clinical trials and adjusted according to the specific situation of the patient.

How is the regulatory effect of IL35 on immune cells realized? 07/15/2022

The IL35 works by regulating the function and activity of immune cells, thereby influencing the immune response of the immune system.

What is the effect of recombinant IL35 on the immune system? 03/14/2022

Recombinant IL35 can inhibit the activity of the immune system, thereby regulating the inflammatory response and the function of immune cells.

Can recombinant IL35 be used with other drugs? 08/11/2021

Combination use of IL35 needs to be evaluated in clinical practice to determine possible interactions and safety.

How to evaluate the efficacy of IL35? 10/06/2020

The efficacy of IL35 is typically evaluated by biomarkers in clinical trials, degree of disease remission, and patient feedback.

Can recombinant IL35 treat autoimmune diseases? 01/20/2020

IL35 shows potential to treat certain autoimmune diseases, but further research is needed to determine its effectiveness and safety.

Customer Reviews (3)

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Reviews
11/23/2021

    IL34 can maintain its biological activity and structural integrity under specific experimental conditions.

    11/17/2021

      IL35 has high chemical and physical stability and is suitable for long-term storage and use.

      12/20/2019

        Products undergo strict quality control to ensure the consistency and stability of each batch.

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