Active Recombinant Human CX3CL1, HIgG1 Fc-tagged
Cat.No. : | CX3CL1-286H |
Product Overview : | The extracellular domain of human CX3CL1 (AAH01163.1) (Gln25-Gly100) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
- Specification
- Gene Information
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Description : | CX3CL1 (chemokine (C-X3-C motif) ligand 1) is a protein-coding gene. Diseases associated with CX3CL1 include pityriasis rosea, and rheumatoid vasculitis, and among its related super-pathways are MIF Mediated Glucocorticoid Regulation and Chemokine signaling pathway. GO annotations related to this gene include chemokine activity and receptor binding |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CX3CR1. |
Molecular Mass : | 35 KDa (monomer) |
AA Sequence : | Gln25-Gly100 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CX3CL1 chemokine (C-X3-C motif) ligand 1 [ Homo sapiens ] |
Official Symbol : | CX3CL1 |
Synonyms : | CX3CL1; chemokine (C-X3-C motif) ligand 1; SCYD1, small inducible cytokine subfamily D (Cys X3 Cys), member 1 (fractalkine, neurotactin); fractalkine; ABCD 3; C3Xkine; CXC3; CXC3C; neurotactin; NTN; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); NTT; SCYD1; ABCD-3; |
Gene ID : | 6376 |
mRNA Refseq : | NM_002996 |
Protein Refseq : | NP_002987 |
MIM : | 601880 |
UniProt ID : | P78423 |
Chromosome Location : | 16q13 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem; |
Function : | chemokine activity; protein binding; receptor binding; |
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◆ Lysates | ||
CX3CL1-840CCL | Recombinant Canine CX3CL1 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCX3CL1 is involved in pain modulation, and its dysregulation is associated with neuropathic pain conditions. Understanding its role may lead to the development of novel analgesic therapies.
Yes, several clinical trials are investigating the therapeutic potential of targeting CX3CL1 in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
CX3CL1 contributes to inflammation in cardiovascular diseases and affects vascular function. Studying its role helps in understanding the pathophysiology of conditions like atherosclerosis.
CX3CL1 acts as a chemoattractant, facilitating the recruitment and activation of immune cells at the site of inflammation, playing a pivotal role in immune response regulation.
Researchers are exploring CX3CL1 as a potential biomarker for diseases such as rheumatoid arthritis and certain cancers, aiming to develop diagnostic tools and monitor disease progression.
Customer Reviews (3)
Write a reviewthe CX3CL1 protein's compatibility with various experimental techniques further supports its usability.
One of the standout features of the CX3CL1 protein is the excellent technical support provided by the manufacturer.
Whether I need to study protein-protein interactions, protein localization, or protein folding, the CX3CL1 protein consistently delivers precise and meaningful data.
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