| Description : |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form. |
| Source : |
Yeast |
| Species : |
Swine |
| Form : |
Lyophilized without carrier protein. |
| Molecular Mass : |
Swine GM-CSF has a predicted molecular weight of 14.4 kDa. |
| AA Sequence : |
APTRPPSPVT RPWQHVDAIK EALSLLNNSN DTAAVMNETV DVVCEMFDPQ EPTCVQTRLN LYKQGLRGSL TRLKSPLTLL AKHYEQHCPL TEETSCETQS ITFKSFKDSL NKFLFTIPFD CWGPVKK |
| Purity : |
>95% as visualized by SDS-PAGE analysis. |
| Applications : |
The GM-CSF protein can be used in cell culture, as a GM-CSF ELISA Standard, and as a Western Blot Control. |
| Storage : |
Stable for up to twelve months from date of receipt at -20?C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20?C. Avoid repeated freeze/thaw cycles. |
| Reconstitution : |
Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
