Recombinant Rat MSR1 cell lysate
Cat.No. : | MSR1-800RCL |
Product Overview : | Rat MSR1 / SCARA1 derived in Human Cells. The whole cell lysate is provided in 1X Sample Buffer.Browse all transfected cell lysate positive controls |
- Specification
- Gene Information
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Source : | Human cells |
Species : | Rat |
Preparation method : | Transfected cells were cultured for 48hrs before collection. The cells were lysed in modified RIPA buffer with cocktail of protease inhibitors. Cell debris was removed by centrifugation and then centrifuged to clarify the lysate. The cell lysate was boiled for 5 minutes in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% b-mercaptoethanol, and lyophilized. |
Lysis buffer : | Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF |
Quality control Testing : | 12.5% SDS-PAGE Stained with Coomassie Blue |
Recommended Usage : | 1. Centrifuge the tube for a few seconds and ensure the pellet at the bottom of the tube.2. Re-dissolve the pellet using 200μL pure water and boiled for 2-5 min.3. Store it at -80°C. Recommend to aliquot the cell lysate into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.Notes:The lysate is ready to load on SDS-PAGE for Western blot application. If dissociating conditions are required, add reducing agent prior to heating. |
Stability : | Samples are stable for up to twelve months from date of receipt at -80°C |
Storage Buffer : | 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF |
Storage Instruction : | Lysate samples are stable for 12 months from date of receipt when stored at -80°C. Avoid repeated freeze-thaw cycles. Prior to SDS-PAGE fractionation, boil the lysate for 5 minutes. |
Gene Name : | Msr1 macrophage scavenger receptor 1 [ Rattus norvegicus ] |
Official Symbol : | MSR1 |
Synonyms : | MSR1; macrophage scavenger receptor 1; macrophage scavenger receptor types I and II; RGD1564316; |
Gene ID : | 498638 |
mRNA Refseq : | NM_001191939 |
Protein Refseq : | NP_001178868 |
Pathway : | Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; |
Function : | low-density lipoprotein particle binding; low-density lipoprotein particle binding; molecular_function; scavenger receptor activity; |
Products Types
◆ Recombinant Protein | ||
MSR1-103H | Recombinant Human MSR1 Protein, His-tagged | +Inquiry |
MSR1-01H | Active Recombinant Human MSR1 Protein, Fc-tagged | +Inquiry |
MSR1-2090H | Recombinant Human MSR1 Protein, MYC/DDK-tagged | +Inquiry |
MSR1-385H | Recombinant Human MSR1 Protein, His-tagged | +Inquiry |
MSR1-2026H | Recombinant Human MSR1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MSR1-2844HCL | Recombinant Human MSR1 cell lysate | +Inquiry |
MSR1-2288MCL | Recombinant Mouse MSR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMSR1 (Macrophage Scavenger Receptor 1) is involved in the recognition and clearance of modified low-density lipoproteins (LDL) by macrophages, playing a critical role in lipid homeostasis.
MSR1 contributes to the resolution of inflammation by promoting the clearance of apoptotic cells and debris. Its anti-inflammatory effects involve modulating cytokine production and signaling.
MSR1 participates in antigen presentation by macrophages, influencing T-cell activation. This role connects MSR1 to adaptive immune responses.
MSR1 is involved in the clearance of amyloid-beta peptides associated with neurodegenerative diseases such as Alzheimer's. Its role in phagocytosis and clearance is crucial in the context of neuroinflammation.
MSR1 modulates the immune response by regulating inflammatory signaling pathways. Its involvement in recognizing modified LDL in atherosclerotic plaques links it to inflammation and atherosclerosis.
Customer Reviews (3)
Write a reviewNo more worries about protein sourcing. This product is a lifesaver in the lab.
Outstanding service! Quick response to inquiries and prompt shipping. A+
This is a must-have in any lab. Consistent quality and great results every time.
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