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Recombinant Human LYVE1, GST-tagged

Cat.No. : LYVE1-48H
Product Overview : Recombinant Human Soluble LYVE1 fused to a GST-tagged produced inE.Coliis a single, non-glycosylated, polypeptide containing 243-323 amino acids and having a total molecular mass of 36 kDa. The LYVE-1 is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : LYVE1-48H
Description : LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Source : Escherichia Coli.
Purity : Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Physical Appearance : Sterile Filtered colorless solution.
Formulation : Recombinant Human LYVE-1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Storage : LYVE-1 although stable at 15°Cfor 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 [ Homo sapiens ]
Synonyms : LYVE1; lymphatic vessel endothelial hyaluronan receptor 1; HAR; XLKD1; LYVE-1; CRSBP-1; hyaluronic acid receptor; extracellular link domain containing 1; extracellular link domain-containing 1; cell surface retention sequence binding protein-1;CRSBP1; UNQ230/PRO263; Extracellular link domain-containing protein 1
Gene ID : 10894
mRNA Refseq : NM_006691
Protein Refseq : NP_006682
MIM : 605702
UniProt ID : Q9Y5Y7
Chromosome Location : 11p15
Function : Binding; hyaluronic acid binding; transmembrane receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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