Recombinant Human MAP2K3 293 Cell Lysate
Cat.No. : | MAP2K3-4511HCL |
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- Gene Information
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Description : | Antigen standard for mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant A is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | MAP2K3 mitogen-activated protein kinase kinase 3 [ Homo sapiens ] |
Official Symbol : | MAP2K3 |
Synonyms : | MAP2K3; mitogen-activated protein kinase kinase 3; PRKMK3; dual specificity mitogen-activated protein kinase kinase 3; dual specificity mitogen activated protein kinase kinase 3; MAP kinase kinase 3; MAPK/ERK kinase 3; MAPKK3; MEK3; MKK3; MEK 3; MAPKK 3; SAPK kinase 2; stress-activated protein kinase kinase 2; SAPKK2; SAPKK-2; |
Gene ID : | 5606 |
mRNA Refseq : | NM_002756 |
Protein Refseq : | NP_002747 |
MIM : | 602315 |
UniProt ID : | P46734 |
Chromosome Location : | 17q11.2 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; CDC42 signaling events, organism-specific biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Cellular roles of Anthrax toxin, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; |
Function : | ATP binding; MAP kinase kinase activity; nucleotide binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; |
Products Types
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Map2k3-3922M | Recombinant Mouse Map2k3 Protein, Myc/DDK-tagged | +Inquiry |
MAP2K3-2016C | Recombinant Chicken MAP2K3 | +Inquiry |
MAP2K3-5005H | Recombinant Human MAP2K3 Protein (Val99-Leu343), N-His tagged | +Inquiry |
◆ Lysates | ||
MAP2K3-4510HCL | Recombinant Human MAP2K3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionEvidence suggests that MAP2K3 expression levels can correlate with disease prognosis, aiding in predicting outcomes for some cancers.
Clinical trials investigating the efficacy of targeting MAP2K3 in cancer treatments are underway, assessing its potential as a therapeutic target.
MAP2K3 dysregulation has been observed in various cancers, including colorectal, lung, and breast cancers.
While specific inhibitors for MAP2K3 are under development, some drugs indirectly impact its activity by targeting related proteins in the signaling cascade.
Expression levels of MAP2K3 can be assessed through techniques like immunohistochemistry or molecular analyses in patient samples.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to customer satisfaction extends beyond providing the protein itself.
They offer comprehensive technical support, including responsive customer service, availability of product information, and timely delivery of the product.
MAP2K3 protein offers numerous advantages in trials, ranging from its stability and bioactivity to the manufacturer's commitment to customer support.
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