Recombinant Human Protein Kinase C, Beta, 2-671aa, His-tagged
Cat.No. : | PRKCB-59H |
Product Overview : | Recombinant Human protein kinase C, beta produced inSf9is a glycosylated, polypeptide chain containing amino acids 2-671 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag. PKC-is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PRKCB-59H |
Description : | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. |
Source : | Sf9 insect cells. |
Unit Definition : | The Unit Definition is 2500 units/mg. One unit of PKCβΙ activity transfers 1 nmole of phosphate to a PKC substrate peptide per minute at 30°C. Recombinant human active PKCβΙ also phosphorylates full length myelin basic protein, histone, and α pseudosubstrate peptide. Activity requires incubation with lipid activators, and may vary depending on the substrate and reaction conditions. |
Purity : | Greater than 95% as determined by SDS-PAGE. |
Formulation : | PKC-is supplied at a of 0.1mg/ml in 10mM Tris, pH 7.4, 0.1M NaCl, 20% glycerol, 1mM DTT, 0.1mM EDTA, 0.2mM PMSF and 0.03% Brij-35. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
Gene Name : | PRKCB protein kinase C, beta [ Homo sapiens ] |
Synonyms : | PRKCB; protein kinase C, beta;PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta;Protein kinase C beta type;EC2.7.11.13; PKC-B; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide |
Gene ID : | 5579 |
mRNA Refseq : | NM_002738 |
Protein Refseq : | NP_002729 |
UniProt ID : | P05771 |
MIM : | 176970 |
Chromosome Location : | 16p12 |
Pathway : | B cell receptor signaling pathway; Calcium signaling pathway; Chemokine signaling pathway; ErbB signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Glioma; GnRH signaling pathway; Leukocyte transendothelial migration; Long-term depression; Long-term potentiation; Non-small cell lung cancer; Pathways in cancer; Phosphatidylinositol signaling system; Tight junction; VEGF signaling pathway; Vascular smooth muscle contraction; Vibrio cholerae infection; Wnt signaling pathway; Hemostasis; Synaptic Transmission |
Function : | ATP binding; calcium ion binding; nucleotide binding; protein binding; protein kinase C activity; transferase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
PRKCB-4336R | Recombinant Rat PRKCB Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKCB-0186H | Recombinant Human PRKCB Protein (A2-V671), GST tagged | +Inquiry |
Prkcb-5118M | Recombinant Mouse Prkcb Protein, Myc/DDK-tagged | +Inquiry |
PRKCB-3423R | Recombinant Rhesus Macaque PRKCB Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKCB-1764H | Recombinant Human PRKCB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRKCB-2859HCL | Recombinant Human PRKCB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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