Recombinant Human FGF1 293 Cell Lysate
Cat.No. : | FGF1-6252HCL |
- Specification
- Gene Information
- Related Products
Description : | Antigen standard for fibroblast growth factor 1 (acidic) (FGF1), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1 (acidic); FGFA; fibroblast growth factor 1; AFGF; ECGF; ECGF beta; ECGFA; ECGFB; endothelial cell growth factor; alpha; beta; FGF alpha; GLIO703; HBGF1; heparin binding growth factor 1; heparin-binding growth factor 1; beta-endothelial cell growth factor; endothelial cell growth factor, beta; endothelial cell growth factor, alpha; FGF-1; HBGF-1; ECGF-beta; FGF-alpha; |
Gene ID : | 2246 |
mRNA Refseq : | NM_000800 |
Protein Refseq : | NP_000791 |
MIM : | 131220 |
UniProt ID : | P05230 |
Chromosome Location : | 5q31.3-q33.2 |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; |
Function : | S100 alpha binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; protein binding; protein tyrosine kinase activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.
Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.
FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.
Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.
Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.
Customer Reviews (3)
Write a reviewBy using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.
The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.
As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.
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