Recombinant Human MMP-13
Cat.No. : | MMP13-42H |
Product Overview : | Recombinant full-length human proMMP-13 (EC 3.4.24.--) expressed in Spodoptera frugiperda Sf9. Swiss Prot P45452 |
- Specification
- Gene Information
- Related Products
Source : | Spodoptera frugiperda |
Species : | Human |
Form : | 50 mM Tris pH 8.0, 800 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2, 0.01% Brij-35. |
Purity : | >95%, homogenous by SDS-PAGE |
Storage : | The enzyme can be kept at -80°C for many month. Repeated freezing and thawing must be avoided. Dilute and activate only the amount of enzyme you need, do not store enzyme in reaction buffer. The active 48 kDa enzyme undergoes very fast changes into a 30 kDa form which still retains enzymatic characteristics of the 48 kDa enzyme. |
Gene Name : | MMP13 matrix metallopeptidase 13 (collagenase 3) [ Homo sapiens ] |
Official Symbol : | MMP13 |
Synonyms : | MMP13; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); collagenase 3; CLG3; MMP-13; MANDP1; |
Gene ID : | 4322 |
mRNA Refseq : | NM_002427 |
Protein Refseq : | NP_002418 |
MIM : | 600108 |
UniProt ID : | P45452 |
Chromosome Location : | 11q22.3 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; |
Function : | calcium ion binding; calcium-dependent protein binding; fibronectin binding; low-density lipoprotein particle receptor binding; metalloendopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
MMP13-5420H | Active Recombinant Human MMP13 Protein | +Inquiry |
MMP13-4451H | Recombinant Human MMP13 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP13-239H | Recombinant Active Human MMP13 Protein, His-tagged(C-ter) | +Inquiry |
MMP13-43H | Active Recombinant Human MMP-13, activated | +Inquiry |
MMP13-2765H | Recombinant Human MMP13 protein(361-430 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
MMP13-4280HCL | Recombinant Human MMP13 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (5)
Ask a questionYes, targeting MMP13 has been explored as a potential therapeutic strategy to inhibit cancer metastasis and invasion.
Yes, MMP13 has been implicated in cardiovascular diseases by contributing to the remodeling of blood vessels and cardiac tissues.
MMP13 facilitates tumor invasion and metastasis by breaking down the extracellular matrix and promoting the migration of cancer cells.
Certain genetic variations in the MMP13 gene have been linked to increased susceptibility to diseases such as osteoarthritis and cancer.
Some clinical trials are investigating drugs that specifically target MMP13 in various cancer types to assess their efficacy and safety.
Customer Reviews (3)
Write a reviewIts reliability and versatility make it an essential tool for investigating MMP13 protein's expression, function, and structural characteristics.
The use of MMP13 protein in this technique allows researchers to explore the intricate three-dimensional structure of the protein at a molecular level.
MMP13 protein is highly recommended for researchers due to its excellent performance in WB experiments and its utility in protein electron microscopy structure analysis.
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