Recombinant Human FASN cell lysate
Cat.No. : | FASN-597HCL |
- Specification
- Gene Information
- Related Products
Description : | The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | FASN fatty acid synthase [ Homo sapiens ] |
Official Symbol : | FASN |
Synonyms : | FASN; fatty acid synthase; FAS; SDR27X1; short chain dehydrogenase/reductase family 27X; member 1; short chain dehydrogenase/reductase family 27X, member 1; OA-519; MGC14367; MGC15706; |
Gene ID : | 2194 |
mRNA Refseq : | NM_004104 |
Protein Refseq : | NP_004095 |
MIM : | 600212 |
UniProt ID : | P49327 |
Chromosome Location : | 17q25 |
Pathway : | ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, conserved biosystem; Fatty acid biosynthesis, elongation, organism-specific biosystem; Fatty acid biosynthesis, elongation, conserved biosystem; |
Function : | 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-malonyltransferase activity; acyl carrier activity; cofactor binding; enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; fatty acid synthase activity; hydrolase activity, acting on ester bonds; lyase activity; myristoyl-[acyl-carrier-protein] hydrolase activity; nucleotide binding; oleoyl-[acyl-carrier-protein] hydrolase activity; oxidoreductase activity; palmitoyl-[acyl-carrier-protein] hydrolase activity; phosphopantetheine binding; protein binding; transferase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
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FASN-2924H | Recombinant Human FASN Protein, His (Fc)-Avi-tagged | +Inquiry |
FASN-3121M | Recombinant Mouse FASN Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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