Recombinant Human L3MBTL1 cell lysate

• Cat.No.: L3MBTL1-964HCL

Specification

• Description: This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: L3MBTL1 l(3)mbt-like 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: L3MBTL1
• Synonyms: L3MBTL1; l(3)mbt-like 1 (Drosophila); l(3)mbt (Drosophila) like , l(3)mbt like (Drosophila) , L3MBTL; lethal(3)malignant brain tumor-like protein 1; dJ138B7.3; DKFZp586P1522; KIAA0681; lethal (3) malignant brain tumor l(3); l(3)mbt protein homolog; L3MBTL; H-L(3)MBT; FLJ41181
• Gene ID: 26013
• mRNA Refseq: NM_015478
• Protein Refseq: NP_056293
• MIM: 608802
• UniProt ID: Q9Y468
• Chromosome Location: 20q13.12
• Function: SAM domain binding; chromatin binding; histone binding; identical protein binding; metal ion binding; methylated histone residue binding; methylated histone residue binding; nucleosomal histone binding; nucleosome binding; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding