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Recombinant Human POLB cell lysate

Cat.No. : POLB-1388HCL
  • Specification
  • Gene Information
  • Related Products
Description : In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance. Also see POLA (MIM 312040).
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : POLB polymerase (DNA directed), beta [ Homo sapiens ]
Official Symbol : POLB
Synonyms : POLB; polymerase (DNA directed), beta; DNA polymerase beta; DNA pol beta; DNA polymerase beta subunit; MGC125976;
Gene ID : 5423
mRNA Refseq : NM_002690
Protein Refseq : NP_002681
MIM : 174760
UniProt ID : P06746
Chromosome Location : 8p12-p11
Pathway : BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function : DNA-directed DNA polymerase activity; damaged DNA binding; enzyme binding; lyase activity; metal ion binding; microtubule binding; nucleotidyltransferase activity; protein binding; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Reviews
09/07/2023

    Efficacy: The enzyme is still active and I am currently using it in some DNA repair assays. It works very well for single nucleotide insertions in gapped DNA which is mostly what I have been using it for recently.
    Quality: Very happy with the quality and longevity. I think the enzyme is ~1yr old with frequent usage and it is still working fine.
    Overall Experience: Very happy. When we need more polB/hUNG, and potentially others, we will purchase from you again.

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