Recombinant Human TNNI3 cell lysate
Cat.No. : | TNNI3-1803HCL |
- Specification
- Gene Information
- Related Products
Description : | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | TNNI3 troponin I type 3 (cardiac) [ Homo sapiens ] |
Official Symbol : | TNNI3 |
Synonyms : | TNNI3; troponin I type 3 (cardiac); troponin I, cardiac; troponin I, cardiac muscle; CMH7; TNNC1; RCM1; cTnI; CMD2A; CMD1FF; MGC116817; |
Gene ID : | 7137 |
mRNA Refseq : | NM_000363 |
Protein Refseq : | NP_000354 |
MIM : | 191044 |
UniProt ID : | P19429 |
Chromosome Location : | 19q13.4 |
Pathway : | Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem; |
Function : | actin binding; calcium channel inhibitor activity; calcium-dependent protein binding; protein binding; protein domain specific binding; protein kinase binding; troponin C binding; troponin T binding; |
Products Types
◆ Recombinant Protein | ||
TNNI3-2254H | Recombinant Human TNNI3 Protein, MYC/DDK-tagged | +Inquiry |
Tnni3-6569M | Recombinant Mouse Tnni3 Protein, Myc/DDK-tagged | +Inquiry |
TNNI3-095H | Recombinant Human TNNI3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
TNNI3-2682H | Recombinant Human TNNI3 protein(61-130 aa), C-His-tagged | +Inquiry |
TNNI3-5866R | Recombinant Rat TNNI3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
TNNI3-223H | Native Human Troponin I Type 3 (Cardiac) | +Inquiry |
TNNI3-01H | Native Human TNNI3 Protein | +Inquiry |
TNNI3-221H | Native Human TNNI3 | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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