Recombinant Human WEE1 cell lysate

• Cat.No.: WEE1-1930HCL

Specification

• Description: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: WEE1 WEE1 homolog (S. pombe) [ Homo sapiens ]
• Official Symbol: WEE1
• Synonyms: WEE1; WEE1 homolog (S. pombe); wee1+ (S. pombe) homolog; wee1-like protein kinase; wee1A kinase; WEE1+ homolog; WEE1A; WEE1hu; FLJ16446; DKFZp686I18166
• Gene ID: 7465
• mRNA Refseq: NM_001143976
• Protein Refseq: NP_001137448
• MIM: 193525
• UniProt ID: P30291
• Chromosome Location: 11p15.3-p15.1
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex, organism-specific biosystem
• Function: ATP binding; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein tyrosine kinase activity