Recombinant Human AKR1C2, MYC/DDK-tagged
Cat.No. : | AKR1C2-18H |
Product Overview : | Recombinant Human AKR1C2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 Mm glycine, 10% glycerol. |
Molecular Mass : | 36.6 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | AKR1C2 aldo-keto reductase family 1, member C2 [ Homo sapiens ] |
Official Symbol : | AKR1C2 |
Synonyms : | DD; DD2; TDD; BABP; DDH2; HBAB; HAKRD; MCDR2; SRXY8; AKR1C-pseudo; aldo-keto reductase family 1 member C2; DD-2; DD/BABP; 3-alpha-HSD3; pseudo-chlordecone reductase; type II dihydrodiol dehydrogenase; chlordecone reductase homolog HAKRD; testicular 17,20-desmolase deficiency; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III |
Gene ID : | 1646 |
mRNA Refseq : | NM_001354 |
Protein Refseq : | NP_001345 |
MIM : | 600450 |
UniProt ID : | P52895 |
Chromosome Location : | 10p15-p14 |
Pathway : | Benzo(a)pyrene metabolism, organism-specific biosystem; Chemical carcinogenesis, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem |
Function : | alditol:NADP+ 1-oxidoreductase activity; bile acid binding; carboxylic acid binding |
Products Types
◆ Recombinant Protein | ||
AKR1C2-01H | Recombinant Human AKR1C2 Protein, DYKDDDDK-tagged | +Inquiry |
AKR1C2-255R | Recombinant Rat AKR1C2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AKR1C2-858H | Recombinant Human AKR1C2 Protein, His-tagged | +Inquiry |
AKR1C2-0452H | Recombinant Human AKR1C2 Protein (Met1-Tyr323 ), Tag Free | +Inquiry |
AKR1C2-456H | Recombinant Human AKR1C2, His tagged | +Inquiry |
◆ Lysates | ||
AKR1C2-8930HCL | Recombinant Human AKR1C2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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