Recombinant Human FH, His-tagged
Cat.No. : | FH-165H |
Product Overview : | Recombinant Human Fumarase /FH Protein (rh Fumarase /FH) Ala 45 - Lys 510 (Accession # AAH03108) was produced in E.coli cells. |
- Specification
- Gene Information
- Related Products
Description : | Fumarate hydratase, mitochondrial is also known as Fumarase or FH, which belongs to the class-II fumarase/aspartase family and Fumarase subfamily. Fumarase is a homotetramer protein which is expressed in red blood cells. There are two substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. Fumarase also acts as a tumor suppressor. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rh Fumarase /FH is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 51 kDa. The predicted N-terminus is Ala 45. DTT-reduced Protein migrates as 47 kDa in SDS-PAGE. |
Endotoxin : | Less than 1.0 EU per μg of the rh Fumarase /FH by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | FH fumarate hydratase [ Homo sapiens ] |
Official Symbol : | FH |
Synonyms : | FH; fumarate hydratase; fumarate hydratase, mitochondrial; fumarase; MCL; LRCC; HLRCC; MCUL1; |
Gene ID : | 2271 |
mRNA Refseq : | NM_000143 |
Protein Refseq : | NP_000134 |
MIM : | 136850 |
UniProt ID : | P07954 |
Chromosome Location : | 1q42.1 |
Pathway : | Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, second carbon oxidation, 2-oxoglutarate =>oxaloacetate, organism-specific biosystem; Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate, conserved biosystem; Citric acid cycle (TCA cycle), organism-specific biosystem; |
Function : | fumarate hydratase activity; lyase activity; |
Products Types
◆ Recombinant Protein | ||
FH-0278H | Recombinant Human FH Protein (A45-K510), Tag Free | +Inquiry |
FH-0279H | Recombinant Human FH Protein (A45-K510), His tagged | +Inquiry |
FH-270C | Recombinant Cynomolgus Monkey FH Protein, His (Fc)-Avi-tagged | +Inquiry |
FH-4158H | Recombinant Human FH Protein, GST-tagged | +Inquiry |
FH-1175H | Active Recombinant Human FH protein, His-tagged | +Inquiry |
◆ Native Protein | ||
fH-10R | Native Rat fH Protein | +Inquiry |
◆ Lysates | ||
FH-6227HCL | Recombinant Human FH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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