Recombinant Human TMED4, Fc-tagged
Cat.No. : | TMED4-181H |
Product Overview : | Recombinant Human TMED4 /ERS25 Protein,With C-Fc Tag (rh TMED4 / ERS25 Fc Chimera) Leu 30 - Arg 194 (Accession # AAH57851) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Transmembrane emp24 domain-containing protein 4 ( TMED4) is also known as Endoplasmic reticulum stress-response protein 25 (ERS25), GMP25iso, p24 family protein alpha-3 (p24alpha3), which belongs to the EMP24/GP25L family. TMED4 is involved in vesicular protein trafficking, mainly in the early secretory pathway. TMED4 appears to play a role in the biosynthesis of secreted cargo including processing. TMED4 is also involved in endoplasmic reticulum stress response, and may play a role in the regulation of heat-shock response and apoptosis. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rh TMED4 / ERS25 Fc Chimera is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 45.9 kDa. The predicted N-terminus is Leu 30. DTT-reduced Protein migrates as 48 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the rh TMED4 / ERS25 Fc Chimera by the LAL method. |
Purity : | >92% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | TMED4 transmembrane emp24 protein transport domain containing 4 [ Homo sapiens ] |
Official Symbol : | TMED4 |
Synonyms : | TMED4; transmembrane emp24 protein transport domain containing 4; transmembrane emp24 domain-containing protein 4; HNLF; GMP25iso; p24alpha3; p24 family protein alpha-3; putative NFkB activating protein HNLF; putative NF-kappa-B-activating protein 156; endoplasmic reticulum stress-response protein 25 kDa; ERS25; |
Gene ID : | 222068 |
mRNA Refseq : | NM_182547 |
Protein Refseq : | NP_872353 |
MIM : | 612038 |
UniProt ID : | Q7Z7H5 |
Chromosome Location : | 7p13 |
Function : | signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
TMED4-4567R | Recombinant Rhesus Macaque TMED4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TMED4-9269M | Recombinant Mouse TMED4 Protein, His (Fc)-Avi-tagged | +Inquiry |
TMED4-3298H | Recombinant Human TMED4 protein(Met1-Arg194), His-tagged | +Inquiry |
TMED4-361Z | Recombinant Zebrafish TMED4 | +Inquiry |
TMED4-3273H | Recombinant Human TMED4, GST-tagged | +Inquiry |
◆ Lysates | ||
TMED4-867HCL | Recombinant Human TMED4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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