Recombinant Human IL18R1, His-tagged
Cat.No. : | IL18R1-191H |
Product Overview : | Recombinant Human IL18R1 /CD218a Protein (rh IL18R1 /CD218a) Ala 19 - Arg 329 (Accession # AAH69575) was produced in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-18 receptor 1 (IL18R1) is also known as CD218 antigen-like family member A (CD218a), IL1 receptor-related protein (IL-1Rrp or IL1R-rp), CDw218a, IL18Ra, IL1RRP, which belongs to the interleukin-1 receptor family. IL18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL18R1 is receptor for interleukin 18 (IL-18). IL18R1 binds to the agonist leads to the activation of NF-kappa-B, but does not bind IL1A/interleukin-1 alpha or IL1B/interleukin-1 beta. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Molecular Mass : | rh IL18R1 /CD218a is fused with polyhistidine tag at the C-terminus, and has a calculated MW of 36.6 kDa. The predicted N-terminus is Ala 19. DTT-reduced Protein migrates as 60-70 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg of the rh IL18R1 /CD218a by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC). |
Reconstitution : | See Certificate of Analysis for reconstitution instructions and specific concentrations. |
Gene Name : | IL18R1 interleukin 18 receptor 1 [ Homo sapiens ] |
Official Symbol : | IL18R1 |
Synonyms : | IL18R1; interleukin 18 receptor 1; interleukin-18 receptor 1; CD218a; IL 1Rrp; IL1RRP; IL-18R1; IL1R-rp; IL-18R-1; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A; IL18RA; CDw218a; IL-1Rrp; |
Gene ID : | 8809 |
mRNA Refseq : | NM_003855 |
Protein Refseq : | NP_003846 |
MIM : | 604494 |
UniProt ID : | Q13478 |
Chromosome Location : | 2q12 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL12 signaling mediated by STAT4, organism-specific biosystem; IL12-mediated signaling events, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; |
Function : | interleukin-1 receptor activity; receptor activity; transmembrane signaling receptor activity; |
Products Types
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Il18r1-1667R | Recombinant Rat Il18r1 Protein, His&GST-tagged | +Inquiry |
IL18R1-314H | Recombinant Human IL18R1 Protein, Fc-tagged | +Inquiry |
IL18R1-1666H | Recombinant Human IL18R1 Protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
IL18R1-2587HCL | Recombinant Human IL18R1 cell lysate | +Inquiry |
IL18R1-2785MCL | Recombinant Mouse IL18R1 cell lysate | +Inquiry |
IL18R1-829RCL | Recombinant Rat IL18R1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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