Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-097-1828   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Human CTSD, His-tagged

Recombinant Human CTSD, His-tagged

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GST(1)
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His(10)
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Cat.No.:
CTSD-218H
Product Overview:
Recombinant Human CTSD MS Standard Protein, C13 and N15-labeled (CTSD / Cathepsin D, Heavy Labeled) Ser 19 - Leu 412 (Accession # NP_001900) was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain >99% incorpor
Description:
Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extrcellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Source:
HEK293
Species:
Human
Tag:
His
Form:
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass:
CTSD / Cathepsin D, Heavy Labeled is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 43.6 kDa. The predicted N-terminus is Ser 19. DTT-reduced Protein migrates as 45-55 kDa in SDS-PAGE due to glycosylation.CTSD / Cathepsin D,
Endotoxin:
Less than 1.0 EU per μg of the CTSD / Cathepsin D, Heavy Labeled by the LAL method.
Purity:
>95% as determined by SDS-PAGE.
Storage:
Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4oC); After reconstitution under sterile conditions for 3 months (-70oC).
Reconstitution:
See Certificate of Analysis for reconstitution instructions and specific concentrations.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-097-1828
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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