Recombinant Human FAM20C, GST-tagged

• Cat.No.: FAM20C-203H
• Product Overview: Recombinant Human FAM20C(1 a.a. - 570 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Description: This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome.
• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 89.1 kDa
• AA Sequence: MVFLVACALHIALDLLPRLERRGAR PSGEPGCSCAQPAAEVAAPGWAQVR GRPGEPPAASSAAGDAGWPNKHTLR ILQDFSSDPSSNLSSHSLEKLPPAA EPAERALRGRDPGALRPHDPAHRPL LRDPGPRRSESPPGPGGDASLLARL FEHPLYRVAVPPLTEEDVLFNVNSD TRLSPKAAENPDWPHAGAEGAEFLS PGEAAVDSYPNWLKFHIGINRYELY SRHNPAIEALLHDLSSQRITSVAMK SGGTQLKLIMTFQNYGQALFKPMKQ TREQETPPDFFYFSDYERHNAEIAA FHLDRILDFRRVPPVAGRMVNMTKE IRDVTRDKKLWRTFFISPANNICFY GECSYYCSTEHALCGKPDQIEGSLA AFLPDLSLAKRKTWRNPWRRSYHKR KKAEWEVDPDYCEEVKQTPPYDSSH RILDVMDMTIFDFLMGNMDRHHYET FEKFGNETFIIHLDNGRGFGKYSHD ELSILVPLQQCCRIRKSTYLRLQLL AKEEYKLSLLMAESLRGDQVAPVLY QPHLEALDRRLRVVLKAVRDCVERN GLHSVVDDDLDTEHRAASAR
• Applications: ELISA; WB-Re; AP; Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FAM20C family with sequence similarity 20, member C [ Homo sapiens (human) ]
• Official Symbol: FAM20C
• Synonyms: FAM20C; family with sequence similarity 20, member C; dentin matrix protein 4; DKFZp547D065; DMP4; IMAGE:4942737; RNS; DMP-4; GEF-CK; extracellular serine/threonine protein kinase FAM20C; dentin matrix protein 4; golgi-enriched fraction casein kinase; NP_064608.2; EC 2.7.11.1
• Gene ID: 56975
• mRNA Refseq: NM_020223
• Protein Refseq: NP_064608
• MIM: 611061
• UniProt ID: Q8IXL6
• Chromosome Location: 7p22.3
• Function: calcium ion binding; protein serine/threonine kinase activity