Recombinant Human EBI3
Cat.No. : | EBI3-45H |
Product Overview : | Recombinant Human EBI3 was expressed in yeast. |
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- Gene Information
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Description : | Epstein-Barr virus induced gene 3 was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a secreted glycoprotein, which is a member of the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). It plays a role in regulating cell-mediated immune responses.EBI3 is a subunit in 2 distinct heterodimeric cytokines: interleukin-27 (IL27) and IL35.IL27 is composed of p28 (IL27) and EBI3. IL27 can trigger signaling in T cells, B cells, and myeloid cells. IL35, an inhibitory cytokine involved in regulatory T-cell function, is composed of EBI3 and the p35 subunit of IL12.Interleukin-27 (IL-27) is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (IL-27B) and IL27-p28 (known as IL-30). |
Source : | Yeast |
Species : | Human |
Form : | Lyophilized from sterile 20mM PB,240mM NaCl,PH6.0. |
Molecular Mass : | 24.8kDa |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE |
Applications : | Western blotting, ELISA |
Storage : | Store it under sterile conditions at -20℃ to -98℃ upon receiving.Recommend to aliquot the protein into smaller quantities for optimal storage. |
Gene Name : | EBI3 Epstein-Barr virus induced 3 [ Homo sapiens ] |
Official Symbol : | EBI3 |
Synonyms : | EBI3; Epstein-Barr virus induced 3; interleukin-27 subunit beta; IL27 subunit; IL35 subunit; cytokine receptor; IL-27 subunit beta; EBV-induced gene 3 protein; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL27B; IL-27B; |
Gene ID : | 10148 |
mRNA Refseq : | NM_005755 |
Protein Refseq : | NP_005746 |
MIM : | 605816 |
UniProt ID : | Q14213 |
Chromosome Location : | 19p13 |
Pathway : | IL27-mediated signaling events, organism-specific biosystem; |
Function : | cytokine activity; cytokine receptor activity; interleukin-27 receptor binding; |
Products Types
◆ Lysates | ||
EBI3-240HCL | Recombinant Human EBI3 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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