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Recombinant Human CAPN2 protein, His-tagged

Cat.No. : CAPN2-122H
Product Overview : Recombinant Human CAPN2 Protein (20-700 aa) is produced by E. coli expression system. This protein is fused with a His tag at the N-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein.
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Source : E. coli
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 82.1 kDa
Protein length : 20-700 aa
AA Sequence : SHDRAIKYLNQDYEALRNECLEAGT LFQDPSFPAIPSALGFKELGPYSSK TRGIEWKRPTEICADPQFIIGGATR TDICQGALGDCWLLAAIASLTLNEE ILARVVPLNQSFQENYAGIFHFQFW QYGEWVEVVVDDRLPTKDGELLFVH SAEGSEFWSALLEKAYAKINGCYEA LSGGATTEGFEDFTGGIAEWYELKK PPPNLFKIIQKALQKGSLLGCSIDI TSAADSEAITFQKLVKGHAYSVTGA EEVESNGSLQKLIRIRNPWGEVEWT GRWNDNCPSWNTIDPEERERLTRRH EDGEFWMSFSDFLRHYSRLEICNLT PDTLTSDTYKKWKLTKMDGNWRRGS TAGGCRNYPNTFWMNPQYLIKLEEE DEDEEDGESGCTFLVGLIQKHRRRQ RKMGEDMHTIGFGIYEVPEELSGQT NIHLSKNFFLTNRARERSDTFINLR EVLNRFKLPPGEYILVPSTFEPNKD GDFCIRVFSEKKADYQAVDDEIEAN LEEFDISEDDIDDGFRRLFAQLAGE DAEISAFELQTILRRVLAKRQDIKS DGFSIETCKIMVDMLDSDGSGKLGL KEFYILWTKIQKYQKIYREIDVDRS GTMNSYEMRKALEEAGFKMPCQLHQ VIVARFADDQLIIDFDNFVRCLVRL ETLFKIFKQLDPENTGTIELDLISW LCFSVL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Gene Name : CAPN2 calpain 2, (m/II) large subunit [ Homo sapiens ]
Official Symbol : CAPN2
Synonyms : CAPN2; CANPL2; CANPml; mCANP; CANP 2; M-calpain; calpain M-type; CANP2; FLJ39928;
Gene ID : 824
mRNA Refseq : NM_001146068
Protein Refseq : NP_001139540
MIM : 114230
UniProt ID : P17655

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is CAPN2 protein expression regulated in normal physiological conditions? 10/15/2021

CAPN2 activity is tightly regulated by intracellular calcium levels and various other factors to maintain cellular homeostasis.

How does CAPN2 protein interact with other molecules or proteins in disease contexts? 03/10/2021

CAPN2 interacts with various cellular proteins, contributing to processes like protein degradation, cytoskeletal remodeling, and cell signaling, influencing disease pathways.

Can CAPN2 protein serve as a potential therapeutic target? 01/02/2018

Research suggests that modulating CAPN2 activity could be a potential therapeutic strategy for managing diseases associated with its dysregulation.

Are there any drugs or compounds known to modulate CAPN2 activity? 07/17/2017

Some compounds and inhibitors targeting CAPN2 have been developed in preclinical studies, showing promise in controlling its activity for therapeutic purposes.

Can CAPN2 protein levels serve as a biomarker for certain diseases? 06/07/2017

In some cases, altered levels of CAPN2 have been observed in disease states, suggesting its potential as a biomarker, but further validation is needed.

Customer Reviews (3)

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03/05/2020

    The CAPN2 protein has been extensively studied and validated in various experimental applications.

    08/03/2019

      Their team of technical experts possess deep knowledge and expertise regarding the protein, ensuring that researchers receive accurate and timely assistance.

      10/01/2017

        In addition to its advantages in trials, the manufacturer of the CAPN2 protein offers exceptional support to researchers.

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