Recombinant Human CTGF, His-tagged

• Cat.No.: CTGF-16H
• Product Overview: Recombinant human CTGF, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid, In 20mM Tris-HCl (pH8.0) containing 10% glycerol
• Molecular Mass: 37.7kDa (344aa)
• Protein length: 27-349aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MQNCSGPCRC PDEPAPRCPA GVSLVLDGCG CCRVCAKQLG ELCTERDPCD PHKGLFCDFG SPANRKIGVCTAKDGAPCIF GGTVYRSGES FQSSCKYQCT CLDGAVGCMP LCSMDVRLPS PDCPFPRRVK LPGKCCEEWV CDEPKDQTVV GPALAAYRLEDTFGPDPTMI RANCLVQTTE WSACSKTCGM GISTRVTNDN ASCRLEKQSR LCMVRPCEAD LEENIKKGKK CIRTPKISKP IKFELSGCTSMKTYRAKFCG VCTDGRCCTP HRTTTLPVEF KCPDGEVMKK NMMFIKTCAC HYNCPGDNDI FESLYYRKMY GDMA
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by BCA assay)

Gene Information

• Gene Name: CTGF connective tissue growth factor [ Homo sapiens ]
• Official Symbol: CTGF
• Synonyms: CTGF; connective tissue growth factor; IGFBP8, CCN2; NOV2; HCS24; MGC102839; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; OTTHUMP00000017213; Hypertrophic chondrocyte-specific protein 24
• Gene ID: 1490
• mRNA Refseq: NM_001901
• Protein Refseq: NP_001892
• MIM: 121009
• UniProt ID: P29279
• Chromosome Location: 6q23.1
• Pathway: Fatty acid, triacylglycerol, and ketone body metabolism; Hippo signaling pathway; PPARA activates gene expression
• Function: growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding