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Recombinant Human CTGF, Fc-tagged

Cat.No. : CTGF-2606H
Product Overview : Recombinant Human CTGF is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln27-Ala349 ) of Human CTGF fused with a FC tag at the C-terminus.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.
Source : human cells
Species : Human
Tag : Fc
Form : Lyophilized from a 0.2 μM filtered solution of PBS,pH 7.4
AA Sequence : QNCSGPCRCPDEPAPRCPAGVSLVL DGCGCCRVCAKQLGELCTERDPCDP HKGLFCDFGSPANRK IGVCTAKDGAPCIFGGTVYRSGESF QSSCKYQCTCLDGAVGCMPLCSMDV RLPSPDCPFPRRVKL PGKCCEEWVCDEPKDQTVVGPALAA YRLEDTFGPDPTMIRANCLVQTTEW SACSKTCGMGISTRV TNDNASCRLEKQSRLCMVRPCEADL EENIKKGKKCIRTPKISKPIKFELS GCTSMKTYRAKFCGV CTDGRCCTPHRTTTLPVEFKCPDGE VMKKNMMFIKTCACHYNCPGDNDIF ESLYYRKMYGDMAVD DIEGRMDEPKSCDKTHTCPPCPAPE LLGGPSVFLFPPKPKDTLMISRTPE VTCVVVDVSHEDPEV KFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKV SNKALPAPIEKTISK AKGQPREPQVYTLPPSREEMTKNQV SLTCLVKGFYPSDIAVEWESNGQPE NNYKTTPPVLDSDGS FFLYSKLTVDKSRWQQGNVFSCSVM HEALHNHYTQKSLSLSPGK
Endotoxin : Less than 0.1 ng/µg (1 IEU/µg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Shipping : The product is shipped at ambient temperature.
Gene Name : CTGF connective tissue growth factor [ Homo sapiens ]
Official Symbol : CTGF
Synonyms : CTGF; connective tissue growth factor; IGFBP8, CCN2; NOV2; HCS24; MGC102839; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; OTTHUMP00000017213; Hypertrophic chondrocyte-specific protein 24
Gene ID : 1490
mRNA Refseq : NM_001901
Protein Refseq : NP_001892
MIM : 121009
UniProt ID : P29279
Chromosome Location : 6q23.1
Pathway : Fatty acid, triacylglycerol, and ketone body metabolism; Hippo signaling pathway; PPARA activates gene expression
Function : growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How can CTGF be measured or detected in clinical settings? 12/20/2017

CTGF levels can be measured using various techniques, including enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry.

What are the potential diagnostic applications of CTGF in medicine? 07/18/2017

CTGF levels can serve as diagnostic markers for fibrotic diseases, aiding in the early detection and monitoring of such conditions.

Are there therapeutic implications of targeting CTGF in clinical practice? 03/08/2017

Yes, targeting CTGF is being explored as a potential therapeutic strategy to mitigate fibrosis in various organs and tissues.

In which medical specialties is CTGF protein research particularly relevant? 11/18/2016

CTGF protein research is particularly relevant in specialties such as rheumatology, pulmonology, and dermatology due to its implications in fibrotic diseases.

How does CTGF contribute to fibrosis? 09/13/2016

CTGF plays a crucial role in promoting the formation of fibrous tissue by stimulating the production of extracellular matrix proteins.

Customer Reviews (3)

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Reviews
03/22/2021

    Its purity, stability, and consistency ensure reliable and reproducible results, giving me confidence in the integrity of my research findings.

    08/06/2019

      With their assistance, I can overcome obstacles and optimize my experimental setup.

      09/23/2018

        With the CTGF protein and the manufacturer's support, I am confident in obtaining accurate and meaningful results for my scientific investigations.

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