Recombinant Human CTGF, Fc-tagged
Cat.No. : | CTGF-2606H |
Product Overview : | Recombinant Human CTGF is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln27-Ala349 ) of Human CTGF fused with a FC tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. |
Source : | human cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from a 0.2 μM filtered solution of PBS,pH 7.4 |
AA Sequence : | QNCSGPCRCPDEPAPRCPAGVSLVL DGCGCCRVCAKQLGELCTERDPCDP HKGLFCDFGSPANRK IGVCTAKDGAPCIFGGTVYRSGESF QSSCKYQCTCLDGAVGCMPLCSMDV RLPSPDCPFPRRVKL PGKCCEEWVCDEPKDQTVVGPALAA YRLEDTFGPDPTMIRANCLVQTTEW SACSKTCGMGISTRV TNDNASCRLEKQSRLCMVRPCEADL EENIKKGKKCIRTPKISKPIKFELS GCTSMKTYRAKFCGV CTDGRCCTPHRTTTLPVEFKCPDGE VMKKNMMFIKTCACHYNCPGDNDIF ESLYYRKMYGDMAVD DIEGRMDEPKSCDKTHTCPPCPAPE LLGGPSVFLFPPKPKDTLMISRTPE VTCVVVDVSHEDPEV KFNWYVDGVEVHNAKTKPREEQYNS TYRVVSVLTVLHQDWLNGKEYKCKV SNKALPAPIEKTISK AKGQPREPQVYTLPPSREEMTKNQV SLTCLVKGFYPSDIAVEWESNGQPE NNYKTTPPVLDSDGS FFLYSKLTVDKSRWQQGNVFSCSVM HEALHNHYTQKSLSLSPGK |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | CTGF connective tissue growth factor [ Homo sapiens ] |
Official Symbol : | CTGF |
Synonyms : | CTGF; connective tissue growth factor; IGFBP8, CCN2; NOV2; HCS24; MGC102839; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; OTTHUMP00000017213; Hypertrophic chondrocyte-specific protein 24 |
Gene ID : | 1490 |
mRNA Refseq : | NM_001901 |
Protein Refseq : | NP_001892 |
MIM : | 121009 |
UniProt ID : | P29279 |
Chromosome Location : | 6q23.1 |
Pathway : | Fatty acid, triacylglycerol, and ketone body metabolism; Hippo signaling pathway; PPARA activates gene expression |
Function : | growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding |
Products Types
◆ Recombinant Protein | ||
CTGF-1313R | Recombinant Rat CTGF Protein, His (Fc)-Avi-tagged | +Inquiry |
CTGF-1287H | Recombinant Human CTGF Protein, His&GST-tagged | +Inquiry |
CTGF-391H | Recombinant Human CTGF Protein, His & Avi-tagged, Unconjugated | +Inquiry |
CTGF-2069H | Recombinant Human CTGF Protein, GST-tagged | +Inquiry |
CTGF-2795H | Recombinant Human CTGF Protein, His-tagged, OVA Conjugated | +Inquiry |
◆ Lysates | ||
CTGF-7205HCL | Recombinant Human CTGF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCTGF levels can be measured using various techniques, including enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry.
CTGF levels can serve as diagnostic markers for fibrotic diseases, aiding in the early detection and monitoring of such conditions.
Yes, targeting CTGF is being explored as a potential therapeutic strategy to mitigate fibrosis in various organs and tissues.
CTGF protein research is particularly relevant in specialties such as rheumatology, pulmonology, and dermatology due to its implications in fibrotic diseases.
CTGF plays a crucial role in promoting the formation of fibrous tissue by stimulating the production of extracellular matrix proteins.
Customer Reviews (3)
Write a reviewIts purity, stability, and consistency ensure reliable and reproducible results, giving me confidence in the integrity of my research findings.
With their assistance, I can overcome obstacles and optimize my experimental setup.
With the CTGF protein and the manufacturer's support, I am confident in obtaining accurate and meaningful results for my scientific investigations.
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