Recombinant Human ABCB7, GST-tagged
Cat.No. : | ABCB7-23H |
Product Overview : | Recombinant Human ABCB7(39 a.a. - 753 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 104.39 kDa |
AA Sequence : | PQWRPHQLGALGTARAYQQIPESLK SITWQRLGKGNSGQFLDAAKALQVW PLIEKRTCWHGHAGGGLHTDPKEGL KDVDTRKIIKAMLSYVWPKDRPDLR ARVAISLGFLGGAKAMNIVVPFMFK YAVDSLNQMSGNMLNLSDAPNTVAT MATAVLIGYGVSRAGAAFFNEVRNA VFGKVAQNSIRRIAKNVFLHLHNLD LGFHLSRQTGALSKAIDRGTRGISF VLSALVFNLLPIMFEVMLVSGVLYY KCGAQFALVTLGTLGTYTAFTVAVT RWRTRFRIEMNKADNDAGNAAIDSL LNYETVKYFNNERYEAQRYDGFLKT YETASLKSTSTLAMLNFGQSAIFSV GLTAIMVLASQGIVAGTLTVGDLVM VNGLLFQLSLPLNFLGTVYRETRQA LIDMNTLFTLLKVDTQIKDKVMASP LQITPQTATVAFDNVHFEYIEGQKV LSGISFEVPAGKKVAIVGGSGSGKS TIVRLLFRFYEPQKGSIYLAGQNIQ DVSLESLRRAVGVVPQDAVLFHNTI YYNLLYGNISASPEEVYAVAKLAGL HDAILRMPHGYDTQVGERGLKLSGG EKQRVAIARAILKDPPVILYDEATS SLDSITEETILGAMKDVVKHRTSIF IAHRLSTVVDADEIIVLDQGKVAER GTHHGLLANPHSIYSEMWHTQSSRV QNHDNPKWEAKKENISKEEERKKLQ EEIVNSVKGCGNCSC |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 [ Homo sapiens ] |
Official Symbol : | ABCB7 |
Synonyms : | ABCB7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ABC7; ATP-binding cassette sub-family B member 7, mitochondrial; ASAT; Atm1p; EST140535 |
Gene ID : | 22 |
mRNA Refseq : | NM_004299 |
Protein Refseq : | NP_004290 |
MIM : | 300135 |
UniProt ID : | O75027 |
Chromosome Location : | Xq13.3 |
Pathway : | ABC transporters; ABC-family proteins mediated transport; Cytosolic iron-sulfur cluster assembly |
Function : | ATP binding; ATPase activity, coupled to transmembrane movement of substances; heme transporter activity |
Products Types
◆ Recombinant Protein | ||
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ABCB7-192M | Recombinant Mouse ABCB7 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABCB7-1094M | Recombinant Mouse ABCB7 Protein | +Inquiry |
ABCB7-8126H | Recombinant Human ABCB7 protein, His & T7-tagged | +Inquiry |
ABCB7-0225H | Recombinant Human ABCB7 Protein (Val472-Cys752), N-His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionYou can communicate with our technical experts who can help you choose the right product.
Yes, this result is caused by post-translational modification, post-translational cleavage, splice variants, etc.
You can communicate with us about the specific customization requirements, and then we will provide you with product price information.
Our recombinant protein products are accompanied by detailed product instructions, and you can contact our technical experts at any time if you have any questions after receiving the product.
Two of the ABCB7 protein products we provide require custom production, and the prices vary according to custom needs, but we can provide you with price information for the other 5 protein products.
Yes, we can customize recombinant protein products with different purity.
There is information in our product manuals, or you can ask our experts about it.
Our customers purchased ABCB7 for ELISA and obtained satisfactory experimental results.
We will send you product price information.
Yes, we offer ABCB7 protein ready for western blotting.
Customer Reviews (4)
Write a reviewGreat protein, works great for WB.
The content of the product manual is very detailed, which provides help for the use of protein products.
High protein purity, fast delivery.
The technicians answered my questions in a timely manner and provided me with some professional advice.
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