Recombinant Human EHMT2, FLAG-tagged

• Cat.No.: EHMT2-41H
• Product Overview: Recombinant Human EHMT2 was expressed in Sf9 cells and contains an N-terminal FLAG tag.

Specification

• Description: G9a is a histone methyltransferase that is specific to lysine 9 of histone H3 (H3K9). Methylation of H3K9 is a signal of transcriptional repression.
• Source: Sf9 insect cells
• Species: Human
• Tag: FLAG
• Form: 20 mM Tris-HCl pH 7.4, 150 mM NaCl and 20% glycerol.
• Molecular Mass: 134 kDa
• Applications: Enzyme kinetics, inhibitor screening, and selectivity profiling.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: 1.5 mg/ml

Gene Information

• Gene Name: EHMT2 euchromatic histone-lysine N-methyltransferase 2 [ Homo sapiens ]
• Official Symbol: EHMT2
• Synonyms: EHMT2; euchromatic histone-lysine N-methyltransferase 2; BAT8, C6orf30, chromosome 6 open reading frame 30 , HLA B associated transcript 8; histone-lysine N-methyltransferase EHMT2; Em:AF134726.3; G9A; KMT1C; NG36/G9a; protein G9a; H3-K9-HMTase 3; G9A histone methyltransferase; HLA-B associated transcript 8; HLA-B-associated transcript 8; lysine N-methyltransferase 1C; ankyrin repeat-containing protein; histone H3-K9 methyltransferase 3; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; BAT8; GAT8; NG36; C6orf30; FLJ35547; DKFZp686H08213
• Gene ID: 10919
• mRNA Refseq: NM_006709
• Protein Refseq: NP_006700
• MIM: 604599
• UniProt ID: Q96KQ7
• Chromosome Location: 6p21.3
• Pathway: Gene Expression, organism-specific biosystem; Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I Transcription Initiation, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem
• Function: histone methyltransferase activity (H3-K27 specific); histone methyltransferase activity (H3-K9 specific); metal ion binding; methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltransferase activity; transferase activity; zinc ion binding