Human C-Reactive Protein Reference standard

• Cat.No.: CRP-78H
• Product Overview: Calibrant for C-reactive protein assays.

Specification

• Species: Human
• Enzyme Unit: 49 milli-International Units (IU) per ampoule.
• Usage: No attempt should be made to weigh out any portion of the freeze-dried material prior to reconstitution. For all practical purposes each ampoule contains the same amount of the same materials. Dissolve the total contents in a known amount of suitable buffer solution with carrier protein (free of peptidase), where extensive dilution is required, to minimise loss by surface adsorption. For economy of use it is recommended that the solution be subdivided into several small containers, which are frozen rapidly to below –40°C and then stored below –40°C in the dark. Repeated freezing and thawing should be avoided.
• Notes: This preparation is not for administration to humans. The preparation contains material of human origin, and either the final product or the source materials, from which it is derived, have been tested and found negative for HBsAg, anti-HIV and HCV RNA. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts.
• Stability: Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities. Reference Materials should be stored on receipt as indicated on the label. Once reconstituted, diluted or aliquoted, users should determine the stability of the material according to their own method of preparation, storage and use.
• Storage: Store at -20°C or below. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature.

Gene Information

• Gene Name: CRP C-reactive protein, pentraxin-related [ Homo sapiens ];
• Official Symbol: CRP
• Synonyms: CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1; MGC88244; MGC149895
• Gene ID: 1401
• mRNA Refseq: NM_000567
• Protein Refseq: NP_000558
• MIM: 123260
• UniProt ID: P02741
• Chromosome Location: 1q21-q23
• Pathway: Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem
• Function: Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity