Human Brain-derived Neurotrophic Factor (rDNA derived) Reference standard
Cat.No. : | BDNF-155H |
Product Overview : | The BDNF used in this preparation is the human form of the molecule with an N-terminal methionine residue, synthesized in E. coli by recombinant DNA technology. |
- Specification
- Gene Information
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Source : | E.coli |
Species : | Human |
Enzyme Unit : | 16 000 units per ampoule. |
Usage : | No attempt should be made to weigh out any portion of the freeze-dried material prior to reconstitution The RR is intended for calibration of local standards. For all practical purposes, each ampoule contains the same quantity of BDNF. The entire contents of each ampoule should be completely dissolved in a known volume of suitable solvent. It is recommended that, when possible, buffer containing carrier protein should be used to minimize loss by surface adsorption. |
Notes : | This preparation is not for administration to humans. The material is not of human or bovine origin. As with all materials of biological origin, this preparation should be regarded as potentially hazardous to health. It should be used and discarded according to your own laboratorys safety procedures. Such safety procedures should include the wearing of protective gloves and avoiding the generation of aerosols. Care should be exercised in opening ampoules or vials, to avoid cuts. |
Stability : | Reference materials are held at Creative Biomart within assured, temperature- controlled storage facilities and they should be stored on receipt as indicated on the label. Accelerated degradation studies have indicated that this material is suitably stable, when stored at -20°C or below, for the assigned values to remain valid until the material is withdrawn or replaced. These studies have also shown that the material is suitably stable for shipment at ambient temperature without any effect on the assigned values. Users who have data supporting any deterioration in the characteristics of any reference preparation are encouraged to contact Creative Biomart. |
Storage : | The ampoules are shipped at ambient temperature. Unopened ampoules should be stored at -20 °C in the dark. For economy of use, it is recommended that the reconstituted solution be subdivided into several small containers and stored at, or below, -40 °C . Repeated freezing and thawing should be avoided. The ampoules do not contain bacteriostat and solutions of the ampouled material should not be assumed to be sterile. Please note: because of the inherent stability of lyophilized material, Creative Biomart may ship these materials at ambient temperature. |
Gene Name : | BDNF brain-derived neurotrophic factor [ Homo sapiens ]; |
Official Symbol : | BDNF |
Synonyms : | BDNF; brain-derived neurotrophic factor; neurotrophin; abrineurin; MGC34632; |
Gene ID : | 627 |
mRNA Refseq : | NM_001143805 |
Protein Refseq : | NP_001137277 |
MIM : | 113505 |
UniProt ID : | P23560 |
Chromosome Location : | 11p14.1 |
Pathway : | Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; |
Function : | growth factor activity; |
Products Types
◆ Recombinant Protein | ||
BDNF-01H | Recombinant Active Human BDNF Protein, His-tagged | +Inquiry |
BDNF-02H | Recombinant Human BDNF Protein, His-tagged | +Inquiry |
BDNF-08H | Recombinant Active Human BDNF Protein, His-tagged(C-ter) | +Inquiry |
BDNF-22H | Recombinant Human BDNF Protein, His-tagged | +Inquiry |
BDNF-312H | Recombinant Human BDNF Protein, His-tagged | +Inquiry |
◆ Lysates | ||
BDNF-001MCL | Recombinant Mouse BDNF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionBDNF levels can be measured through blood tests or cerebrospinal fluid analysis, providing insights into the protein's concentration in the body.
BDNF deficiency has been linked to conditions such as Alzheimer's disease, Parkinson's disease, and depression.
While there are no direct BDNF medications, certain drugs and treatments aim to enhance BDNF levels indirectly, offering potential therapeutic benefits.
Physical exercise has been shown to increase BDNF production, suggesting that exercise could be used as a non-pharmacological intervention to support neurological health.
BDNF is crucial for synaptic plasticity, influencing the strength and efficacy of connections between neurons, which is vital for learning and memory processes.
Customer Reviews (3)
Write a reviewThe BDNF protein is carefully characterized, and its functional properties are well-documented.
With its high purity and bioactivity, BDNF protein ensures reliable and consistent results in a wide range of experimental applications.
The BDNF protein is of exceptional quality and is perfectly suited to meet the experimental needs of researchers.
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