| Cat. No. : |
TrxR-77Y |
| Introduction : |
Thioredoxin reductase (TrxR/NTR), an enzyme belonging to the flavoprotein family of pyridine nucleotide-disulfide oxidoreductases. Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins and participates in the defense system against oxidative stresses. |
| Source : |
Escherichia Coli. |
| Physical Appearance : |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity : |
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Formulation : |
Each mg of protein contains 20 mM phosphate buffer pH 7.4 and 0.15 M sodium chloride. |
| Solubility : |
It is recommended to reconstitute the lyophilized NTR in sterile 18 MΩ-cm H2O. |
| Biological Activity : |
The specific activity was found to be 5 IU/mg. |
| Unit Definition : |
One unit equals the change in absorbance at 412 nm per minute at 25°C using 0.2 mM NADPH containing 5 mM DTNB (pH 7.0) |
| Stability : |
NTR although stable at 4°C for 3 weeks, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. |
| Synonyms : |
Thioredoxin Reductase (NADPH); NTR; TrxR; EC 1.8.1.9; GRIM-12; KDRF; MGC9145; TR; TR1; TRXR1; TXNR; Trxr1; oxidoreductase; Gene associated with retinoid-IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; thioredoxin reductase 1; thioredoxin reductase GRIM-12; thioredoxin-disulfide reductase; NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin:NADP+ oxidoreductase. |
