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Recombinant Human Progesterone receptor LBD/Hsp90 complex, GST-tagged

Cat.No. : PGR-106H
Product Overview : Recombinant Human GST-tagged Progesterone receptor ligand-binding domain (PR-LBD) consists of a 218 a.a. GST tag, a 31 a.a. flexible linker and a 305 a.a. PR-LBD, Acc# NP_000917, amino acids 630-933. A complex of human PR-LBD with human Hsp90 (PR-LBD/Hsp90) was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged PR-LBD and Hsp90 are the major components of the complex.
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Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 5 mM DTT, 7 mM reduced glutathione, 15% glycerol.
Purity : >80%
Applications : Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name : PGR progesterone receptor [ Homo sapiens ]
Official Symbol : PGR
Synonyms : PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3;
Gene ID : 5241
mRNA Refseq : NM_000926
Protein Refseq : NP_000917
MIM : 607311
UniProt ID : P06401
Chromosome Location : 11q22-q23
Pathway : Cellular roles of Anthrax toxin, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem;
Function : DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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