Recombinant Human TNNI2, GST-tagged
Cat.No. : | TNNI2-17H |
Product Overview : | Recombinant Human TNNI2(1 a.a. - 182 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 47.7 kDa |
AA Sequence : | MGDEEKRNRAITARRQHLKSVMLQI AATELEKEESRREAEKQNYLAEHCP PLHIPGSMSEVQELCKQLHAKIDAA EEEKYDMEVRVQKTSKELEDMNQKL FDLRGKFKRPPLRRVRMSADAMLKA LLGSKHKVCMDLRANLKQVKKEDTE KERDLRDVGDWRKNIEEKSGMEGRK KMFESES |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | TNNI2 troponin I type 2 (skeletal, fast) [ Homo sapiens (human) ] |
Official Symbol : | TNNI2 |
Synonyms : | TNNI2; troponin I type 2 (skeletal, fast); troponin I, skeletal, fast; troponin I, fast skeletal muscle; AMCD2B; DA2B; FSSV; troponin I fast twitch 2; troponin I; fast twitch skeletal muscle isoform |
Gene ID : | 7136 |
mRNA Refseq : | NM_003282 |
Protein Refseq : | NP_003273 |
MIM : | 191043 |
UniProt ID : | P48788 |
Chromosome Location : | 11p15.5 |
Pathway : | Muscle contraction; Striated Muscle Contraction |
Function : | contributes_to actin binding; protein binding; troponin T binding |
Products Types
◆ Recombinant Protein | ||
TNNI2-9496M | Recombinant Mouse TNNI2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnni2-6568M | Recombinant Mouse Tnni2 Protein, Myc/DDK-tagged | +Inquiry |
TNNI2-5865R | Recombinant Rat TNNI2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNNI2-15H | Recombinant Human TNNI2, MYC/DDK-tagged | +Inquiry |
TNNI2-1996H | Recombinant Human TNNI2 protein | +Inquiry |
◆ Native Protein | ||
Tnni2-7429M | Native Mouse Tnni2 Protein | +Inquiry |
◆ Lysates | ||
TNNI2-1802HCL | Recombinant Human TNNI2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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