Native Human AMBP

• Cat.No.: AMBP-27H
• Product Overview: Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function. Purified from the urine of patients with chronic renal tubular proteinuria.

Specification

• Species: Human
• Form: Lyophilized from 0.02M NH4HCO3.
• Purity: Greater than 96.0%.
• Applications: Inhibition of stimulation of cultured lymphocytes by protein antigens; induction of cell division of lymphocytes, a mitogenic effect that can either be enhanced or inhibited by the action of other plasma components; inhibition of neutrophil granulocyte migration in vitro; and inhibition of chemotaxis.
• Usage: This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
• Storage: Human A1M although stable at room temperature for 3 weeks, should be stored between 2-8°C.
• Reconstitution: Use phosphate buffer, pH>7.0 containing 0.15M NaCl, is recommended.

Gene Information

• Gene Name: AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens ]
• Official Symbol: AMBP
• Synonyms: AMBP; alpha-1-microglobulin/bikunin precursor; ITI, ITIL; protein AMBP; bikunin; complex forming glycoprotein heterogeneous in charge; EDC1; growth inhibiting protein 19; HCP; HI30; IATIL; inter alpha trypsin inhibitor light chain; ITILC; protein HC; tryp
• Gene ID: 259
• mRNA Refseq: NM_001633
• Protein Refseq: NP_001624
• MIM: 176870
• UniProt ID: P02760
• Chromosome Location: 9q32-q33
• Function: IgA binding; calcium channel inhibitor activity; calcium oxalate binding; heme binding; peptidase inhibitor activity; protein homodimerization activity; serine-type endopeptidase inhibitor activity; transporter activity